Design and Characterization of Phase Transition System of Zolmitriptan Hydrochloride for Nasal Drug Delivery System

Malviya, Vedanshu; Ladhake, V; Gajbiye, K; Satao, J; Tawar, Mukund

doi:10.37285/ijpsn.2020.13.3.8

Cited by 59 publications

(2 citation statements)

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“…Similar research also found in the studies of Akter et al (2021) [2] and Verma et al, (2013) [20] . Malviya et al (2020) [9] revealed that use of coco-peat may be good for improvement of vegetative growth (27.50 maximum branches per plant), [9] reveled that nutrient availability plays pivotal role on production and thus, provision of proper growing media is the pre-requisite for better growth and fruit yield. The growing medium must be porous for root aeration and drainage and thus, capable of water and nutrient retention.…”

Section: Effect Of Growth Media On Growth Parametersmentioning

confidence: 99%

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Standardization of EF polymer as potting media for roof top cultivation of ridge gourd

Meena¹,

Pilania²,

Singh³

et al. 2023

Int. J. Hortic. Food Sci.

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The present study reports that EF polymer in potting media for rooftop cultivation of ridge gourds bestows myriads effect on growth, yield and quality in ridge gourd plants. Here in media of sand + vermicompost + EF polymer + cocopeat + vermiculite and perlite (3: 2.5: 2: 2: 0.5) had significant effect on vine length (426.5cm), number of branches per vine (14.66), early flowering (35.6 days), early picking (95 days), duration of flowering (155.67days), maximum fruit length (22.3cm), fruit diameter (4.2cm) and fruit yield (680.66gm). Similarly, it influences quality parameters such as TSS (4.2°Brix), total sugar (9.15mg/100g), protein content (1.39 mg/100g), vitamin C (4.34mg/100g), reducing sugar (6.58mg/100g), available of nitrogen (0.86%), phosphorus (0.704%) and potassium (1.87%) in leaf as compare to control. Moreover, EF polymer in potting media act as bio stimulant to stimulate the nitrogen content and influence photosynthetic efficiency in ridge gourd.

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Section: Effect Of Growth Media On Growth Parametersmentioning

confidence: 99%

“…(2018) in cucumber, Kasture (2019) [7] in snake gourd and Arain et al (2020) [3] in bottle gourd. Malviya et al (2020) [9] revealed that use of coco-peat may be good for quality (TSS 5.15 o Brix, total sugars 3.97%, Vitamin C 26.07 mg/100 g fruit, though it was at par with vermiculite 26.52 mg/100 g) followed by peat and compost.…”

mentioning

confidence: 99%

Standardization of EF polymer as potting media for roof top cultivation of ridge gourd

Meena¹,

Pilania²,

Singh³

et al. 2023

Int. J. Hortic. Food Sci.

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Development and Evaluation of Fast dissolving Film of Fluoxetine hydrochloride

Malviya

Pande

2021

RJPT

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The intention of the present study was to formulate the oral dispersible film of Fluoxetine hydrochloride using pullulan as a polymer and to evaluate it with the different parameters. The drug-excipients studies were carried out in order to determine any type of incompatibilities by using Fourier transmission infrared spectroscopy (FT-IR). The oral dispersible films were prepared using solvent casting method using pullulan as a polymer. Glycerin was used as a plasticizer. The prepared films were evaluated for the parameters like physical appearance, thickness, folding endurance, In-vitro disintegration, mechanical properties, surface pH, drug content uniformity, taste evaluation, In-vitro dissolution test and stability study. The X5 formulation was found to be stable and appropriate in its evaluation parameters than compared to other formulations. The folding endurance was found to be 259±2.53, disintegration time was found to be 04±0.69, thickness was found to be 0.081±0.003, tensile strength was found to be 5.55, the % elongation was found to be 27.50, the maximum percentage drug release was found to be 95.80% in 30 minutes. The drug content was found to be 99.86 with surface pH of 6.8. In the stability studies of the formulation the product was found to be stable for 90 days. The oral dispersible film is simple to administer and very much effective for the patients and the prepared film of fluoxetine hydrochloride proves to be potential candidate for safe and effective oral dispersible drug delivery.

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Evaluation of Antidepressant activity of Tricholepis glaberrima DC using various Paradigms

Jodh¹,

Tawar²,

Kachewar³

2022

RJPT

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In the present experiment, Tricholepis glaberrima DC has been taken to study its antidepressant activity. The study was carried out in two different doses of the test drug. The animals were divided into 4 groups of 5 animals each, respectively. Mice in Group I (control) and II (standard) were administered distilled water, per oral and Imipramine 10mg/kg, per oral once respectively. Group III and IV were treated with the test drug METG in the dose of 100mg/kg and 300mg/kg, respectively. Findings of the test groups were compared with that of standard as well as plain control groups. In despair swim test and Tail suspension method, METG (100mg/kg and 300mg/kg per oral) depicted significant (*p<0.05 and p<0.01) results, in a dose dependent manner, when compared to vehicle treated group, indicating significant antidepressant activity. The results obtained in the present study for antioxidant activity indicate that the plants of Tricholepis glaberrima DC are a significant source of natural antioxidants. This test reveals the antidepressant activity of Tricholepis glaberrima DC Via serotonergic, adrenergic mechanism in a dose dependent pattern.

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Design and Characterization of Phase Transition System of Zolmitriptan Hydrochloride for Nasal Drug Delivery System

Cited by 59 publications

References 0 publications

Standardization of EF polymer as potting media for roof top cultivation of ridge gourd

Standardization of EF polymer as potting media for roof top cultivation of ridge gourd

Development and Evaluation of Fast dissolving Film of Fluoxetine hydrochloride

Evaluation of Antidepressant activity of Tricholepis glaberrima DC using various Paradigms

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