Derivative spectrophotometry in the analysis of mixtures of cefotaxime sodium and cefadroxil monohydrate

Spectrophotometric Determination Studies of Cefotaxime (CFX) and their CFX- Cd (II) and CFX- Cu (II) Complexes

“…A graph is drawn between the volume of CFX and absorbance 26 . The data are shown in Table 8 and Fig 8. The point of the intersections in graph gives the composition of these complexes [27][28] . It is seen from the figure that Cd and Cu forms 1:1 complex with CFX under these experimental conditions.…”

“…Anions might influence the color formation reaction. Hence, the author has chosen certain bivalent cations and some common anions carry out the interference studies [28][29] on CFX-Cd (II) and CFX -Cu (II) complexes. To know the effect of various cations and anions on the determination of Cd and Cu, We have studied the effect of various metal ions which are usually associated with Cd and Cu.…”

Spectrophotometric Methods as Solutions to Pharmaceutical Analysis of β-Lactam Antibiotics

“… a separation and determination of carbapenem and degradant (e.g., the determination of ertapenem and its degradant) when the substraction technique was used [24-25]  a separation and determination of penam and cephem analogs (e.g., the determination of penicillin-G, penicillin-G procain in the presence of dihydrostreptomycin sulphate salts or the determination of cefotaxime and cefadroxil), cephem analog and inhibitor of -lactamases (e.g., the determination of cephradine and clavulanic acid) and carbapenem analog and degradation products (e.g., the determination of meropenem and its degradant) when ratio spectra of derivative with all orders were used [26][27][28][29]  a separation and determination of carbapenem and degradation products (e.g., the determination of ertapenem) when the substraction technique was used [30]  a separation and determination of carbapenem and degradation products (e.g., the determination of ertapenem) when the Kraise's method was used [31]  a separation and determination of penam analogs (e.g., the determination of ampicillin and flucloxacillin) when multivariate methods (classical least squares and principle component regression) were used.…”

Simultaneous Determination of Cefotaxime Sodium and Paracetamol by LC-MS

“…Cephalosporin antibacterial used in the treatment of infections due to susceptible Gram-positive and Gram-negative bacteria, including infections of the abdomen, bones and joints, CNS, skin and skin structure, genito-urinary tract (including gonorrhoea) and respiratory tract, in gynaecological infections, and in early Lyme disease [2,3]. Literature survey revealed that several HPLC [4][5][6][7][8][9][10][11], HPTLC [12] and spectrophotometric methods [13][14][15][16][17][18] have been used for determination of Cefotaxime Sodium. Paracetamol is chemically 4-hydroxy acetanilide.…”