Der Stoffwechsel von Verbindungen mit Dreifachbindung V. Der Abbau von Diincarbonsäuren und Kohlenwasserstoffen in vivo

Abstract

Summary. 10,12-Hencicosadiynoic acid (I), 5,7-hexadecadiynoic acid (IV), and 10,12-docosadiynedioic acid (VI) were fed to rats. As metabolites 4,6-undecadiynedioic acid (11), 5,7-dodecadiynedioic acid (V), and 4,6-decadiynedioic acid (VII) respectively were isolated from the urine. 10,12-Heptadecadiynoic acid (111) also yielded metabolite 11. Furthermore 9,ll-eicosadiyne (X) and for comparison purposes eicosane (XI), hexadecanedioic acid (VIII), and docosanedioic acid (IX) were fed. X and X I were incorporated into depot fat and liver lipids to a certain degree. The diynes I, 11, IV, and X are new compounds. Untersuchungen iiber das Schicksal von Fettsauren mit Dreifachbindungen imTierkorper, z. B. der Stearol-, Behenol-, Taririn