Depressive Symptoms in Patients with Congenital Heart Disease: Incidence and Prognostic Value of Self-Rating Depression Scales

Kourkoveli, Panagiota; Rammos, S.; Parissis, John; Maillis, Antonis; Kremastinos, Dimitrios Th.; Paraskevaidis, Ioannis

doi:10.1111/chd.12200

Cited by 29 publications

(19 citation statements)

References 39 publications

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“…20 There is also preliminary evidence to suggest that depressive symptoms in adolescents and adults with CHD contribute to poorer clinical cardiac outcomes. 21 However, even in the absence of any link between psychological and medical outcomes, clinical attention to the psychological needs of adults with CHD would be warranted in order to optimize quality of life. 22,23 Our collective responsibility to managing adults with CHD goes beyond reducing cardiac mortality and morbidity.…”

Section: Psychological Distress Among Adults With Chdmentioning

confidence: 99%

An Integrated Adult Congenital Heart Disease Psychology Service

Ferguson

Kovacs

2016

Congenital Heart Disease

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Section: Psychological Distress Among Adults With Chdmentioning

confidence: 99%

An Integrated Adult Congenital Heart Disease Psychology Service

Ferguson

Kovacs

2016

Congenital Heart Disease

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“…A recent Finnish longitudinal developmental study spanning preschool measurement with adulthood indicated that trajectories of steep increases in triglycerides were predictive of depression onset [29]. One prospective study in congenital heart disease for major adverse cardiovascular events (fatal and hospitalization incidences) related to depression indicated ORs 1.6–3.6 for a 5-year period [30]. The cross-sectional fatal SCORE risk in a Finnish regional study for depression was OR 2.9 for males and OR 1.3 for females with 30% of MetS prevalence [31].…”

Section: Discussionmentioning

confidence: 99%

Depression contributing to dyslipidemic cardiovascular risk in the metabolic syndrome

Lemche¹,

Чабан

Lemche

2016

J Endocrinol Invest

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PurposeTriglycerides are considered an emerging risk factor for cardiovascular mortality. Recent evidence relating depression and metabolic syndrome (MetS) implicated triglyceride levels. We thus investigated interrelations of self-reported depression severity (Zung) and MetS-related biological measures with CVD risk estimates in MetS patients.Methods N = 101 patients fulfilling International Diabetes Federation criteria for MetS from a nationwide sampled treatment cohort for MetS with familial T2DM risk or manifest T2DM in a Ukrainian governmental health care system were participants. Both laboratory and non-laboratory measures were included. Recent European cardiological SCORE system CVD risk estimates were used as outcome variables.ResultsFollowing correlation matrix, we entered all variables into principal component analysis (PCA; 76.7% explained variance), followed by hierarchical regression and structural equation modeling (SEM). The PCA suggested a one-factor solution, where the latent variable showed highest loadings of SCORE risk estimates, triglycerides, depression severity, and pulse pressure. A comprehensive SEM was adjusted with 92.7% explained variance: overall CVD risk related to depression, pulse pressure, triglycerides, and fasting glucose.ConclusionThe findings in this MetS sample suggest that triglycerides and depression severity are the key variables among MetS biomarkers in cross-sectionally associating with the fatal and total SCORE risk estimates in MetS. Electronic supplementary materialThe online version of this article (doi:10.1007/s40618-016-0601-y) contains supplementary material, which is available to authorized users.

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“…Findings on the frequency and severity of current anxiety-depressive symptoms assessed by self-report are mixed. Some studies found high symptomatology in adults with CHD (59, 61, 63–65), whereas others did not (66–72). According to several authors (60, 71–74), denial mechanisms or coping strategies are frequently used by CHD patients and could contribute to the favorable psychological outcomes sometimes suggested by self-assessments.…”

Section: Adults With D-tga: Emerging Evidencementioning

confidence: 99%

“…Other studies report that only 11–12% of patients receive psychological counseling, despite high rates of anxiety-depressive syndromes (62, 64). In adults with CHD, presence of a high depressive or anxiety symptomatology is associated with higher rates of unemployment (64), lower quality of life (QoL) (62, 64, 68), greater consumption of tobacco and alcohol (75), poorer adherence to treatment (76), and worse cardiac prognosis (65). …”

Section: Adults With D-tga: Emerging Evidencementioning

confidence: 99%

Neuropsychological and Psychiatric Outcomes in Dextro-Transposition of the Great Arteries across the Lifespan: A State-of-the-Art Review

et al. 2017

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Advances in prenatal diagnosis, perioperative management, and postoperative care have dramatically increased the population of survivors of neonatal and infant heart surgery. The high survival rate of these patients into adulthood has exposed the alarming prevalence of long-term neuropsychological and psychiatric morbidities. Dextro-transposition of the great arteries (d-TGA) is one of the most extensively studied cyanotic congenital heart defect (CHD) with regard to neurodevelopmental outcomes. Landmark studies have described a common neurodevelopmental and behavioral phenotype associated with d-TGA. Children with d-TGA display impairments in key neurocognitive areas, including visual–spatial and fine motor abilities, executive functioning, processing speed, and social cognition. As they grow older, they may face additional challenges with a worsening of deficits in higher order cognitive skills, problems in psychosocial adjustment and a higher-than-expected rate of psychiatric disorders, such as attention-deficit hyperactivity disorder, depression, and anxiety. The aim of this review is to summarize the available recent data on neuropsychological and psychiatric outcomes in individuals with d-TGA after the arterial switch operation. We present findings within a life-span perspective, with a particular emphasis on the emerging literature on adolescent and young adult outcomes. Finally, we propose avenues for future research in the CHD adult neuropsychology field. Among these avenues, we explore the potential mechanisms by which pediatric neurodevelopmental impairments may have lifelong adverse effects as well as alternative interventions that could optimize outcomes.

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Depressive Symptoms in Patients with Congenital Heart Disease: Incidence and Prognostic Value of Self-Rating Depression Scales

Cited by 29 publications

References 39 publications

An Integrated Adult Congenital Heart Disease Psychology Service

An Integrated Adult Congenital Heart Disease Psychology Service

Depression contributing to dyslipidemic cardiovascular risk in the metabolic syndrome

Neuropsychological and Psychiatric Outcomes in Dextro-Transposition of the Great Arteries across the Lifespan: A State-of-the-Art Review

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