Depressive symptoms as an independent risk factor for mortality

Corrêa, Vanessa Pereira; Confortin, Susana Cararo; d’Orsi, Eleonora; Sá-Junior, Antônio Reis de; Oliveira, César de; Schneider, Ione Jayce Ceola

doi:10.1590/1516-4446-2019-0749

Cited by 13 publications

(12 citation statements)

References 35 publications

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“…To the best of our knowledge, this was the first study that compared the prevalence of depression in older nursing home residents living in low-altitude and high-altitude regions. Depression was common (26.9%) in older nursing home residents in China, which is similar to the findings in Brazil (23.5%) ( 29 ), but higher than those living in nursing homes in Japan (11.9%) ( 30 ) and Thailand (18.5%) ( 31 ). However, it should be noted that due to different sampling methods, demographic and clinical characteristics, and measures of depression as well as their cutoff values, direct comparisons should be made with caution ( 8 ).…”

Section: Discussionsupporting

confidence: 78%

Prevalence of Depression in Older Nursing Home Residents in High and Low Altitude Regions: A Comparative Study

et al. 2021

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Objective: Depressive symptoms (depression hereafter) is common in older adults, and closely associated with environmental factors. This study compared the prevalence of depression in older adults living in high-altitude and low-altitude regions, and their association with quality of life (QOL).Method: A total of 632 older nursing home residents were included, with 425 participants living in low-altitude and 207 participants living in high-altitude regions. Depression and QOL were assessed using standardized instruments.Results: The prevalence of depression was 26.9% (95% CI: 23.43–30.37%) in the whole sample of older nursing home residents, with 11.1% (95% CI: 8.01–14.05%) in those living in low-altitude and 59.4% (95% CI: 52.68–66.17%) in those living in high-altitude regions. Multiple logistic regression analysis revealed that living in low-altitude region (P < 0.001, OR = 0.07, 95% CI: 0.04–0.12) was associated with lower risk of depression, while perception of poor health status (P < 0.001, OR = 3.86, 95% CI: 1.98–7.54) and having insomnia (P < 0.001, OR = 4.76, 95% CI: 2.99–7.56) were associated with higher risk of depression. QOL was significantly lower in physical (F(1,632) = 35.421, P < 0.001), psychological (F(1,632) = 20.777, P < 0.001), social (F(1,632) = 8.169, P < 0.001) and environmental domains (F(1,632) = 11.861, P < 0.001) in those with depression.Conclusion: Depression was common in older nursing home residents especially those living in the high-altitude region. Considering the negative impact of depression on QOL and functional outcomes, routine screening and timely treatment of depression should be implemented in this population.

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Section: Discussionsupporting

confidence: 78%

Prevalence of Depression in Older Nursing Home Residents in High and Low Altitude Regions: A Comparative Study

et al. 2021

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“…Late life depression is a major public health concern, due to its significant impact in quality of life, health trajectories and survival [ 16 , 19 , 31 ]. This study sought to examine the gender differences in positive screens and self-reported diagnosis of depression in older adults in Chile, as a contribution to understand the factors involved in underdiagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…Late life depression has a negative impact on quality of life [ 16 , 17 ] and is a risk factor for mortality [ 18 , 19 ]. Nevertheless, there are important barriers to treatment, including underdiagnosis [ 20 – 22 ].…”

Section: Introductionmentioning

confidence: 99%

Gender differences in positive screen for depression and diagnosis among older adults in Chile

2022

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Background Different factors are associated with late life depression and diagnosis, including gender. It has also been reported that depression among older people is underdiagnosed. As a result, the mental health needs of this group are insufficiently met. The aim of this study was to explore gender differences in the factors associated with positive screens for depression and self-reported diagnosis among older adults in Chile. Methods Data from 3786 older adults who participated in the Social Protection Survey in 2016 were analysed. PHQ-9 was used to identify screen-positive cases. Self-reported diagnosis of depression was used to determine the proportion of people with a screen-positive result who had received a diagnosis of depression. Logistic regression models were used to determine sociodemographic and health factors associated with depression and underdiagnosis in older men and women. Results The prevalence of a screen-positive result was 20.91% (5.83% major depressive disorder) among men, and 36.38% (12.43% major depressive disorder) among women. 18.77% of men and 34.11% of women with a positive depression screening had received a diagnosis. More educated men were more likely to receive a diagnosis. Older age was associated with a lower probability of diagnosis among older women. Conclusions Our results suggest that depressive disorders are undiagnosed in a high proportion of older adults in Chile. Gender is a relevant factor in the underdiagnosis of depression in this group. Further research is needed to understand the factors involved in these gaps, to improve detection and provide timely support and treatment.

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“…Sedangkan, penelitian Correa, dkk. 7 menunjukkan bahwa depresi berhubungan dengan peningkatan risiko kematian pada lansia di Brazil. Menurut penelitian Alencar, dkk.…”

Section: Pendahuluanunclassified

“…Depresi berhubungan dengan tingginya risiko infeksi dan kematian pada pasien yang menjalani hemodialisis. 7 Pengaturan diet yang buruk, aktivitas fisik yang rendah, stres, dan ketaatan pasien yang rendah dalam membatasi cairan dan konsumsi obat sering ditemukan pada pasien yang mengalami depresi. Hal ini sangat berpengaruh pada kesehatan pasien.…”

Section: Diskusiunclassified

Peran Gejala Depresi sebagai Faktor Prediktor Kematian dalam Enam Bulan pada Lansia yang Menjalani Hemodialisis

Perdhana¹,

Chasani²,

Mupangati³

et al. 2022

JPDI

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Pendahuluan. Depresi merupakan gangguan mental yang banyak ditemukan baik pada kelompok lansia maupun pada pasien yang menjalani hemodialisis. Depresi berdampak buruk terhadap kualitas hidup pasien. Penelitian yang menghubungkan depresi sebagai faktor prediktor kematian dalam enam bulan pada lansia yang menjalani hemodialisis belum pernah dilakukan di Indonesia. Penelitian ini bertujuan untuk mengetahui peran gejala depresi sebagai faktor prediktor kematian dalam 6 bulan pada lansia yang menjalani hemodialisis.Metode. Penelitian dengan desain kohort prospektif dilakukan pada Februari – Agustus 2020 di Unit Hemodialisis Rumah Sakit Roemani Muhammadiyah Semarang. Adapun kriteria inklusi meliputi lansia (usia ≥60 tahun), menjalani hemodialisis ≥3 bulan, frekuensi hemodialisis 2 kali seminggu, bersedia mengikuti penelitian, dapat berkomunikasi dengan baik, dan tidak terdapat riwayat gangguan mental sebelumnya yang meliputi riwayat gangguan psikotik, dan gangguan mental akibat penggunaan zat. Sedangkan pasien dengan data tidak lengkap, pindah ke unit hemodialisis lain, HBsAg +, kadar Hemoglobin <7 mg/dl, skor RAPUH >2, dan memiliki stressor lain yang tidak terkait dengan hemodialisis atau Penyakit Ginjal Kronis (PGK) seperti faktor sosial, keluarga, dan pekerjaan dieksklusi dari penelitian ini. Depresi dinilai menggunakan kuesioner Beck Depression Inventory-II yang telah diterjemahkan ke dalam Bahasa Indonesia. Adapun pengisian kuesioner dilakukan oleh responden dengan panduan oleh peneliti dalam proses pengisiannya. Data yang terkumpul kemudian dianalisis menggunakan Kaplan Meier dan Cox Regression menggunakan SPSS 18.0.Hasil. Dari total 32 responden, mayoritas adalah laki-laki yaitu sebanyak 26 responden (81,3%). Rerata usia responden adalah 67,2 (simpang baku [SB] 7) tahun. Sebanyak 6 (18,7%) responden mengalami depresi dan 26 (81,3%) responden tidak mengalami depresi. Hasil analisis Cox Regression menunjukkan bahwa depresi berperan sebagai faktor prediktor kematian dalam 6 bulan pada lansia yang menjalani hemodialisis (p=0.012), dan hazard ratio=10,149.Simpulan. Depresi berperan sebagai faktor prediktor kematian dalam 6 bulan pada lansia yang menjalani hemodialisis.Kata Kunci: Depresi, geriatri, mortalitas, penyakit ginjal kronik, penyakit ginjal tahap akhirDepressive symptoms as a Predictor Factor of All-Cause Mortality within Six Months in Elderly Hemodialysis PatientsIntroduction. Depression is a mental disorder that is often found in the elderly and hemodialysis patients, resulting in bad effects on patients. There is no study on the relationship between depression and all-cause mortality risk in elderly hemodialysis patients in Indonesia. This study aimed to determine the role of depression as a predictor factor of all-cause mortality within 6 months in elderly hemodialysis patients. Methods. A prospective cohort study was conducted from February to August 2020 at the hemodialysis unit of Roemani Muhammadiyah Hospital, Semarang. The inclusion criteria were elderly patients (aged ≥60 years), undergoing hemodialysis ≥3 months, hemodialysis frequency twice a week, willing to participate in this study, able to communicate well, and has no history of mental disorders include a history of psychotic disorders and mental disorders due to substance use. Meanwhile, patients whose data were incomplete, transferred to another hemodialysis unit, HBsAg +, hemoglobin level <7 mg/dl. FRAILTY score >2, and had other stressors not related to hemodialysis or chronic kidney disease (CKD) such as social, family, and work factors were excluded from this study. Depression was assessed using the Beck Depression Inventory-II questionnaire. The collected data was then analyzed using Kaplan Meier and Cox Regression.Results. Of 32 respondents, most of them were male (81.3%). The mean age was 67.2 (SD 7) years. There were 6 (18.7%) respondents categorized into a depression group and 26 (81.3%) respondents into a non-depression group. Cox Regression analysis showed that depression was a predicting factor of all-cause mortality within six months in elderly hemodialysis patients (p value=0.012, and Hazard ratio=10.149). Conclusion. Depression is a predictor factor of all-cause mortality within six months in elderly hemodialysis patients.

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Depressive symptoms as an independent risk factor for mortality

Cited by 13 publications

References 35 publications

Prevalence of Depression in Older Nursing Home Residents in High and Low Altitude Regions: A Comparative Study

Prevalence of Depression in Older Nursing Home Residents in High and Low Altitude Regions: A Comparative Study

Gender differences in positive screen for depression and diagnosis among older adults in Chile

Peran Gejala Depresi sebagai Faktor Prediktor Kematian dalam Enam Bulan pada Lansia yang Menjalani Hemodialisis

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