Denture stomatitis in the elderly

Cumming, C. G.; Wight, Christine; Blackwell, C. L.; Wray, D. Walter

doi:10.1111/j.1399-302x.1990.tb00232.x

Cited by 66 publications

(51 citation statements)

References 16 publications

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“…affecting approximately 30 to 75% of otherwise healthy denture wearers and the most common form of oral candidiasis (1,9,10,19,36,46,50). The main causative agent of DS is Candida albicans (38).…”

Section: Enture Stomatitis (Ds) Is An Inflammatory Fungal Infectionmentioning

confidence: 99%

Development of a Contemporary Animal Model of Candida albicans-Associated Denture Stomatitis Using a Novel Intraoral Denture System

et al. 2012

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bDenture stomatitis (DS) is a fungal infection characterized by inflammation of the oral mucosa in direct contact with the denture and affects up to 50% of denture wearers. Despite the prevalence, very little is known about the role of fungal or host factors that contribute to pathogenesis. Recently, we developed a novel intraoral denture system for rodent research. This denture system consists of custom-fitted fixed and removable parts to allow repeated sampling and longitudinal studies. The purpose of this study was to use this denture system to develop a clinically relevant animal model of DS. To establish DS, rats were inoculated with pelleted Candida albicans, which resulted in sustained colonization of the denture and palate for 8 weeks postinoculation. Biofilm formation on the denture was observed by week 4 and on the palate by week 6 postinoculation. Rats were monitored for clinical signs of disease by assigning a clinical score after macroscopic examination of the palate tissue according to Newton's method. By week 4 postinoculation, the majority of inoculated rats with dentures exhibited a clinical score of 1 (pinpoint erythema). By week 6 and week 8 postinoculation, increasing percentages of rats exhibited a clinical score of 2 (diffuse erythema/ edema). Histological analysis of palate tissue demonstrated progressively increasing inflammatory cell recruitment throughout the time course of the infection. Palatal biofilm formation was commensurate with development of palatal erythema, which suggests a role for biofilm in the inflammatory response.

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Section: Enture Stomatitis (Ds) Is An Inflammatory Fungal Infectionmentioning

confidence: 99%

Development of a Contemporary Animal Model of Candida albicans-Associated Denture Stomatitis Using a Novel Intraoral Denture System

et al. 2012

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“…In denture wearers, Candida albicans, a prevalent fungus in the mouth, has been the predominant species identified in cases with clinical signs of DS, which occurrence is often increased almost 3-fold, in geriatric populations (Reichart, 2000;Shulman et al, 2004;MacEntee et al, 1998;Cumming et al, 1990;Frenkel et al, 2000). Candidiasis, a fungal infection, is aggravated by the adhesion of C. albicans to the tissue-fitting surface of a maxillary denture, which serves as an effective reservoir of microorganisms (Budtz-Jorgensen, 1981;Samaranayake et al, 1980;Vasilas et al, 1992;Thein et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

A case study of denture base resins on the adhesion of Candida albicans to prevent denture stomatitis

Al-Awadhi¹,

Cheong²,

Park³

2014

J. Dent. Oral Hyg.

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The objective of this case report was to investigate whether Candida albicans adhesion to the poly(methyl methacrylate) (PMMA) denture surface is reduced by surface modifications in two innovative methods. Three experimental groups on the tissue surface of a maxillary denture consisted of a control (pure PMMA), negatively surface-charged modified-PMMA (mPMMA), and application of a self-bonding polymer (SBP). The results of the clinical report revealed that both mPMMA and SBP groups had reduced amounts of adherent C. albicans on the resin surfaces compared to the control. Interestingly, the SBP demonstrated a reduced amount of C. albicans adherence up to 21 days followup, where the mPMMA group exhibited a longer effect till 30 days.

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“…Denture-induced stomatitis is reported to be an inflammatory reaction of the denture-bearing mucosa, being characterized by different degrees of erythema and affects many complete upper denture wearers [1][2][3] . Despite the multifactorial etiology of this disease, Candida albicans is still reported as the primary etiologic agent 4 .…”

Section: Introductionmentioning

confidence: 99%

Effect of affordable disinfectant solutions on Candida albicans adhered to acrylic resin for dental prosthesis

Hashizume

Hoscharuk

Moreira

2015

RGO, Rev. Gaúch. Odontol.

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ObjectiveTo evaluate the effect of different low-cost disinfectant solutions on Candida albicans (C. albicans) adhered to acrylic resin used in dental prosthesis. Methods Sixty acrylic resin specimens were divided into four experimental groups according to the disinfecting agent tested (2% chlorhexidine, 1% sodium hypochlorite, vinegar and 10v hydrogen peroxide) and two control groups. Fifty specimens were incubated with C. albicans and after immersed in the disinfecting solutions or saline (negative control). Specimens without contamination constituted the positive control group. After disinfection procedures, all specimens were immersed in a culture medium and incubated for 24 hours at 37°C. Culture media turbidity was evaluated. Results The disinfectants 2% chlorhexidine and 1% sodium hypochlorite performed a maximal reduction of C. albicans. Vinegar showed intermediate antifungal effect and 10v hydrogen peroxide showed a lower effect.Conclusions Among the disinfecting solutions tested in the present study, 2% chlorhexidine and 1% sodium hypochlorite are the most effective in the reduction of C. albicans adhered to acrylic resin. However, vinegar may represent a viable and low-cost alternative to prosthesis disinfection.

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Denture stomatitis in the elderly

Cited by 66 publications

References 16 publications

Development of a Contemporary Animal Model of Candida albicans-Associated Denture Stomatitis Using a Novel Intraoral Denture System

Development of a Contemporary Animal Model of Candida albicans-Associated Denture Stomatitis Using a Novel Intraoral Denture System

A case study of denture base resins on the adhesion of Candida albicans to prevent denture stomatitis

Effect of affordable disinfectant solutions on Candida albicans adhered to acrylic resin for dental prosthesis

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