Dendrimer‐Scaffold‐Based Electron‐Beam Patterning of Biomolecules

Bhatnagar, Parijat; Mark, Sonny S.; Kim, Il; Chen, Hongyu; Schmidt, Brad; Lipson, Michal; Batt, Carl A.

doi:10.1002/adma.200501170

Cited by 31 publications

(24 citation statements)

References 53 publications

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“…Spatial binding of biomolecules and quantum dots to PECVD-patterned substrates is demonstrated. Currently, surface patterning of biomolecules involves techniques such as dip-pen nanolithography, [10][11][12] electron- [13] and ion-beam lithography, [14,15] polydimethylsiloxane stamping, [8,16] ink-jet printing, [17] nanoparticle self-assembly, [18] chemical selectivity on patterned gold, [19] and atomic force microscopy (AFM) mediated nanografting. [20,21] These techniques encounter inherent limitations and drawbacks for biomolecular patterning.…”

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confidence: 99%

Site‐Specific Patterning of Biomolecules and Quantum Dots on Functionalized Surfaces Generated by Plasma‐Enhanced Chemical Vapor Deposition

et al. 2006

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Plasma‐enhanced chemical vapor patterned surfaces are used for site‐ specific attachment of biomolecules and semiconductor quantum dots (QDs; see figure). The fabrication of surfaces with multiple functional building blocks can be used in a single step to create complex multifunctional patterned substrates incorporating self‐assembled monolayers (SAMs) and thiol‐functionalized quantum dots for a variety of applications.

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confidence: 99%

Site‐Specific Patterning of Biomolecules and Quantum Dots on Functionalized Surfaces Generated by Plasma‐Enhanced Chemical Vapor Deposition

et al. 2006

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“…[50] It is also possible to chemically modify SAMs in a specific manner by electrons. [33,[52][53][54][55][56][57][58][59] …”

Section: Nanoscaled Lateral Structurization Of Sams For Surface Functmentioning

confidence: 99%

Interfacial Systems Chemistry: Out of the Vacuum—Through the Liquid—Into the Cell

Wöll

2010

ChemPhysChem

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“…However, conventional fabrication methods create relatively homogeneous scaffolds that cannot present the micro-and nanoscale instructive cues to maintain cell phenotype and behavior. To synergistically incorporate the scaffold architecture within the biological materials, several methods, such as nanoimprinting, 5 electron beam lithography, 6 electrospinning, [7][8][9][10][11] solvent casting/salt leaching, 12 gas foaming, 13 phase separation 14,15 and solid freeform fabrication 16 techniques, have been widely used. Nanoimprinting and electron beam lithography are able to precisely fabricate two-dimensional (2D) surface features, but they require long fabrication times, special apparatuses, and expensive instruments.…”

Section: Introductionmentioning

confidence: 99%

Laser-assisted biofabrication in tissue engineering and regenerative medicine

et al. 2016

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Controlling the spatial arrangement of biomaterials and living cells provides the foundation for fabricating complex biological systems. Such level of spatial resolution (less than 10 lm) is difficult to be obtained through conventional cell processing techniques, which lack the precision, reproducibility, automation, and speed required for the rapid fabrication of engineered tissue constructs. Recently, laserassisted biofabrication techniques are being intensively developed with the use of computer-aided processes for patterning and assembling both living and nonliving materials with prescribed 2D or 3D organization. In this review, we discuss laser-assisted fabrication methods, including laser tweezers, multi-photon polymerization, laser-induced forward transfer (LIFT), matrix assisted pulsed laser evaporation (MAPLE), and laser ablation as well as their applications in biological science and biomedical engineering. These advanced technologies enable the precise manipulation of in vitro cellular microenvironments and the ability to engineer functional tissue constructs with high complexity and heterogeneity, which serve in regenerative medicine, pharmacology, and basic cell biology studies.

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Dendrimer‐Scaffold‐Based Electron‐Beam Patterning of Biomolecules

Cited by 31 publications

References 53 publications

Site‐Specific Patterning of Biomolecules and Quantum Dots on Functionalized Surfaces Generated by Plasma‐Enhanced Chemical Vapor Deposition

Site‐Specific Patterning of Biomolecules and Quantum Dots on Functionalized Surfaces Generated by Plasma‐Enhanced Chemical Vapor Deposition

Interfacial Systems Chemistry: Out of the Vacuum—Through the Liquid—Into the Cell

Laser-assisted biofabrication in tissue engineering and regenerative medicine

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