Demonstration of poliovirus in isolated leucocytes, blood and C.S.F. smears of infected monkey by immunofluorescence and biological means

Kovács, E.; Baratawidjaja, R. K.; Walmsley-Hewson, A.; Labzoffsky, N. A.

doi:10.1007/bf01555170

Cited by 14 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Visualization of poliovirus antigen in the leucocytes of infected monkeys by means of immunofluorescence has been recently reported from this laboratory (1). Mention was also made of the preliminary results obtained both with experimental animMs and clinical material in cases of influenza., lymphocytic choriomeningitis, mumps ~nd rabies and the possibility of the application of this method for an early diagnosis of viral infections wus discussed.…”

Section: (Received March 8 1965)mentioning

confidence: 96%

Demonstration of vaccinia, lymphocytic choriomeningitis and rabies viruses in the leucocytes of experimentally infected animals

Baratawidjaja

Morrissey

Labzoffsky

1965

Archiv f Virusforschung

Self Cite

View full text Add to dashboard Cite

Section: (Received March 8 1965)mentioning

confidence: 96%

Demonstration of vaccinia, lymphocytic choriomeningitis and rabies viruses in the leucocytes of experimentally infected animals

Baratawidjaja

Morrissey

Labzoffsky

1965

Archiv f Virusforschung

Self Cite

View full text Add to dashboard Cite

“…Immunofluor escence (IF) techniques, both direct and indirect, have been employed for the diagnosis of various viral infections [1]. In 1963, Kovacs and his associates observed poliovirus IF present in peripheral blood and cerebrospinal fluid (CSF) leukocytes of intracerebrally-inoculated monkeys [2]. In 1966, by in direct fluorescent staining of virus antigens localized in CSF leukocytes, Som mer ville [3] identified coxsackieviruses B 3 and B 5, echovirus 6, mumps virus, and herpes simplex virus.…”

mentioning

confidence: 99%

Rapid Diagnosis of Enterovirus Meningitis by Immunofluorescent Staining of CSF Leukocytes

Taber¹,

Mirkovic²,

Adam³

et al. 1973

Intervirology

View full text Add to dashboard Cite

Indirect immunofluorescence was applied to achieve the rapid diagnosis of enteroviral meningitis within hours of receipt of the specimen. Cerebrospinal fluid (CSF) leukocytes from 40 patients were studied by a method adapted to utilize combination antiserum pools in conjunction with indirect immunofluorescence, and results were compared to those of conventional isolation and serological techniques. When virus was isolated from the CSF (17 patients), there was general agreement with the virus identified by immunofluorescence staining of CSF leukocytes. The advantages of immunofluorescence were particularly striking in 19 patients from whom virus could not be isolated from the CSF and in 4 patients from whom virus could not even be isolated from the throat or rectum. By immunofluorescence, virus was detected in 20 of 21 of these patients. Overall, the rapid immunofluorescence findings were confirmed by the slower conventional methods in 32 of 33 cases. Economy of both time and materials was made practicable by use of the LBM combination antiserum pools, which allow 42 antigenic types to be identified in a single set of 8 simultaneous tests.

show abstract

Rapid identification of neurotropic viruses by an immunofluorescent technique applied to cerebrospinal fluid cellular deposits

Sommerville

1966

Archiv f Virusforschung

View full text Add to dashboard Cite

Demonstration of poliovirus in isolated leucocytes, blood and C.S.F. smears of infected monkey by immunofluorescence and biological means

Cited by 14 publications

References 3 publications

Demonstration of vaccinia, lymphocytic choriomeningitis and rabies viruses in the leucocytes of experimentally infected animals

Demonstration of vaccinia, lymphocytic choriomeningitis and rabies viruses in the leucocytes of experimentally infected animals

Rapid Diagnosis of Enterovirus Meningitis by Immunofluorescent Staining of CSF Leukocytes

Rapid identification of neurotropic viruses by an immunofluorescent technique applied to cerebrospinal fluid cellular deposits

Contact Info

Product

Resources

About