Delayed cure despite early recurrence after pulmonary vein isolation for atrial fibrillation

O’Donnell, David; Furniss, Stephen S.; Dunuwille, Asunga; Bourke, John

doi:10.1016/s0002-9149(02)03005-9

Cited by 96 publications

(109 citation statements)

References 11 publications

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“…Even a single AF episode during the first 2 months reduced this result twice. The available publications during the patient enrolment phase showed no association between early AF recurrence and long-term results [7]. This is opposite to the data presented by Arya et al [16] and Cai et al [6].…”

Section: Late Af Recurrence Risk Factorsmentioning

confidence: 69%

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Does a blanking period after pulmonary vein isolation impact long-term results? Results after 55 months of follow-up

et al. 2014

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Background: The aims of the study are 1) to assess antiarrhythmic prophylaxis efficacy during the first 2 months after radiofrequency ablation (ARF) sustain SR were: males (82.9% vs. 62.2%; p = 0.018), younger patients (44.8 ± 12.7 vs. 52.5 ± 9.9; p = 0.0001), patients with smaller left atrium diameter (4.05 ± ± 0.49 cm vs. 4.25 ± 0.51 cm; p = 0.04), and those without any AF recurrence during the first 2 months after ARF (78.7% vs. 35.6%; p < 0.0001). In the multivariable analysis, the independent risk factors for LAFR were hypertension (p < 0.001) and persistent AF (p = 0.014). Conclusions: Antiarrhythmic prophylaxis does not affect the number of AF recurrences during the first 2 months after ablation. SR maintenance during a blanking period after AF ablation is a positive prognostic factor in long-term follow-up. Persistent AF and hypertension are independent risk factors for late AF recurrence after pulmonary vein isolation. (Cardiol J 2014; 21, 4: 384-391)

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Section: Late Af Recurrence Risk Factorsmentioning

confidence: 69%

“…Furthermore, it is not clearly defined when the early periods ends and when the late period starts. Previously, AF recurrences during the first weeks after PVI were treated as a non-significant factor, but nowadays they are regarded to have an impact on long-term PVI failure [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Does a blanking period after pulmonary vein isolation impact long-term results? Results after 55 months of follow-up

et al. 2014

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“…253,329,436,684,932,935,970,971,972 Because these arrhythmias do not definitively indicate therapy failure over the long term (only half of these patients will manifest later recurrences), this period is also referred to as the blanking or therapy stabilization period. 935,973 It is also important to recognize that the later AF recurrences are observed during the blanking phase, the lower the chance of long-term success.…”

Section: Early Recurrence After Ablationmentioning

confidence: 99%

“…On the other hand, up to 60% of the patients experiencing this event within the first months postablation will not have any further arrhythmias during long-term follow-up. 253,436,970,971,994 Therefore, reablation is not recommended in an ERAF that might be a transient phenomenon. 2 …”

Section: Early Reablationmentioning

confidence: 99%

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Calkins,

Kuck,

Cappato

et al. 2012

Heart Rhythm

1,763

1,468

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“…1 -4 Despite constant improvements in clinical outcomes with advances in ablation devices and techniques, the recurrence of atrial tachyarrhythmia (ATa) after catheter ablation is still an ongoing problem. 5,6 Some researchers 5,6 observed that early recurrence of AF (ERAF) did not affect the longterm outcome of catheter ablation for AF. However, very late recurrence of atrial fibrillation (VLRAF) after catheter ablation has rarely been identified or researched.…”

Section: Introductionmentioning

confidence: 99%

Predictors of Very Late Recurrence of Atrial Fibrillation After Circumferential Pulmonary Vein Ablation

Liu

Dong

et al. 2008

Clinical Cardiology

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Background: Early recurrence of atrial fibrillation (ERAF) after catheter ablation is common and has been thoroughly studied. However, very late recurrence of atrial fibrillation (VLRAF) is rarely researched, and its characteristics have not been determined. Hypothesis: The aim of this study was to investigate the clinical characteristics of VLRAF after circumferential pulmonary vein ablation (CPVA), and to identify the risk factors for VLRAF. Methods: We retrospectively studied 259 consecutive patients with atrial fibrillation (AF) who were referred for CPVA. Clinical variables were investigated and predictors of VLRAF were identified. Results: A total of 249 patients were enrolled in this study. After a mean follow-up of 18.2±4.4 mo, 14 patients (5.6%) had VLRAF. Patients with VLRAF were more likely than those without recurrence to have ERAF (78.6% versus 17.8%, p = 0.000) and persistent AF (50.0% versus 13.0%, p = 0.000), but were less likely to achieve pulmonary vein (PV)

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Delayed cure despite early recurrence after pulmonary vein isolation for atrial fibrillation

Cited by 96 publications

References 11 publications

Does a blanking period after pulmonary vein isolation impact long-term results? Results after 55 months of follow-up

Does a blanking period after pulmonary vein isolation impact long-term results? Results after 55 months of follow-up

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Predictors of Very Late Recurrence of Atrial Fibrillation After Circumferential Pulmonary Vein Ablation

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