volume 27, issue 4, P555-560 2004
DOI: 10.1590/s0100-40422004000400008
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Abstract: Recebido em 2/6/03; aceito em 18/2/04; publicado na web em 17/06/04 DEGRADATION AND STABILIZATION OF DICLOFENAC IN POLYMERIC NANOCAPSULES. The parameters which affect the degradation and stabilization of diclofenac in suspensions of nanocapsules and of the corresponding spray-dried powders were investigated. Formulations were subjected to 14 months of storage at room temperature. In addition, a study of the degradation of diclofenac was carried out by exposing the formulations or mixtures (drug and adjuvants)…

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