1957
DOI: 10.1002/cne.901070103
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Degeneration of retinal ganglion cells in infant chimpanzees reared in darkness

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Cited by 100 publications
(33 citation statements)
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“…28 -30 However, possible involvement of the retina in amblyopia has been controversial. [31][32][33][34][35][36] While several electrophysiological studies showed that pattern electroretinograms and electro-oculograms in amblyopic eyes were reduced compared with normal eyes, 35,36 other studies have not concurred. 33,34 With OCT, the retinal structure can be measured reliably.…”
Section: Discussionmentioning
confidence: 99%
“…28 -30 However, possible involvement of the retina in amblyopia has been controversial. [31][32][33][34][35][36] While several electrophysiological studies showed that pattern electroretinograms and electro-oculograms in amblyopic eyes were reduced compared with normal eyes, 35,36 other studies have not concurred. 33,34 With OCT, the retinal structure can be measured reliably.…”
Section: Discussionmentioning
confidence: 99%
“…However, some animal studies do demonstrate abnormal findings in retinal microstructures, including degeneration of retinal ganglion cells (RGCs),8 9 an increased number of amacrine synapses in the IPL,6 7 a reduction in the number of bipolar synapses in the IPL,6 thinning of the IPL,10 11 decreased nucleolar volume and cytoplasmic cross-sectional area of RGCs,10 and a decrease in the density of Müller fibres 11. We believe that these changes in the retinal microstructure may have occurred in our study participants and may be related to the thinning of the GCL+IPL observed in our study.…”
Section: Discussionmentioning
confidence: 99%
“…The latter limitation is critical for experimental work, such as electrode marking, where the results of one experiment are required in order to plan the next one. The method of double embedding in celloidin and paraffin, as practised by Chow, Riesen & Newell (1957), was likewise too time-consuming. The rapid hot celloidin method of Walls (1932) seemed promising but did not yield good results in our hands.…”
Section: (Received 1 February 1961)mentioning
confidence: 99%