Cytotoxicity of three maleic anhydride copolymers and common solvents used for polymer solvation

Cytotoxic and apoptotic effects of Poly(maleic anhydride-co-vinyl acetate) drug carrier copolymer on MCF-7 and MDA-MB-231 breast cancer cells

“…Karakus and co-workers previously synthesized maleic anhydride copolymers by free-radical copolymerization named as: maleic anhydridevinyl acetate (MAVA) and structural characterizations were carried out by Fourier transform infrared (FTIR) and nuclear magnetic resonance [ 1 H NMR, 13 C NMR, and 13 C-APT (attached-proton test)] spectrometry 10 . They have studied surface morphology by scanning electron microscopy (SEM).…”

“…Methyl ethyl ketone (MEK) was used as organic media presence of benzoyl peroxide (BPO) as the radical initiator for 24 h at 80 °C 8 . Poly (vinyl acetate), was gently removed from the organic media by dissolving the reaction products in ethyl acetate for 24 h. Then the products were dried in a vacuum incubator for 24 h at 55 °C 10 . Units/ml penicillin and 100 μg/ml streptomycin in a 37°C humidified incubator with 5% CO 2 .…”

Methyl methacrylate based copolymers and terpolymers: Preparation, identification, and plasticizing capability for a poly(methyl methacrylate) used in aviation

“…All peaks conforming to the vinyl protons of the monomers disappeared. The signals were the protons from the methyl group of MMA (δ = 1.08 ppm, h), the methylene group of MMA (CH 2 , δ = 1.98 ppm, g), CH 3 on the MI units (δ = 2.20 ppm, f), OCH 3 on MMA (δ = 3.62 ppm, e), CH on the main‐chain backbone of the MAH and MI units (δ = 3073 ppm, d), and the aromatic ring of MI (δ = 7.22 and 8.20 ppm, c, b, and a) …”

“…Also, the peaks of the CAH stretching vibrations of MMA and MAH (2952 cm 21 ) and the asymmetric and symmetric bending vibrations of the ACH 3 and AOCH 3 bonds of the MMA units (1453 and 1385 cm 21 , respectively) appeared; these confirmed the existence of these two monomers in the resulting copolymers. 30,31 So, the copolymerization of MMA with MAH occurred successfully ( Figure 1).…”

In vitro amoebicidal activity of poly(maleic anhydride-co-vinyl acetate) copolymer on Acanthamoeba spp. trophozoites and cysts

“…MAVA copolymer was synthesized by free radical polymerization of maleic anhydride (MA) and vinyl acetate (VA) at 1:1 molar ratio in methyl ethyl ketone (MEK) using benzoyl peroxide (BPO) as an initiator, at 80°C, for 24 h. Detailed information about this process can be found elsewhere [2,21,22]. Briefly, the polymerization of MA (recrystallized from benzene) and VA was carried out in a 100 mL three-necked round-bottom flask.…”