Cytopathological Evaluation of Thyroid by Fine Needle Aspiration Cytology and Correlation with T3 T4 and TSH Levels

Poudel, Suman; Regmi, Sudeep; Shahi, Aakash; Samdurkar, Ashok

doi:10.3126/jucms.v3i4.24267

Cited by 5 publications

(3 citation statements)

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“…Our present study showed that thyroid lesions are common in females with female to male ratio 9 : 1 which is similar to the study done by Poudel et al 12 17 , among the non neoplastic lesion colloid goitre was the common thyroid lesion followed by lymphocytic thyroiditis which had the similarity with the present study.…”

Section: Resultssupporting

confidence: 92%

Evaluation of Different Thyroid Lesions with Fine Needle Aspiration Cytology and Thyroid Function Tests

Ranabhat

Parajuli

Poudel

et al. 2018

J. Gandaki Med. Coll. Nepal

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Introduction: Swelling of the thyroid gland is a commonly encountered clinical problem in all age groups whether benign or malignant. Fine Needle Aspiration Cytology (FNAC) of the thyroid lesions along with hormonal function test helps in the proper preoperative assessment. Ultimately it changes clinical management and improves the patient outcome.Objectives: To describe the cytomorphological features of palpable thyroid nodules using fine needle aspiration cytology (FNAC) along with the assessment of thyroid hormonal status of the patient.Methods: The study was conducted in the Department of Pathology of Gandaki Medical College and Teaching hospital from January 2017 to December 2017 and included 50 patients with thyroid lesions. Cytological assessment was done using FNAC along with serological assessment of thyroid hormones.Results: In the study 50 cases of thyroid swelling were included and evaluated by cytological and hormonal analysis which comprises of 10% males and 90% females with a with a female to male ratio of 9 : 1. Maximum number of cases was seen in the age range 41 - 60 years (46%), mean age being 44.6 years. The cytological diagnosis comprised colloid goiter (58%), lymphocytic thyroiditis (16%), Hashimoto thyroiditis (10%). Thyroid hormone analysis showed 66% euthyroid, 22% hypothyroid and 12% hyperthyroid.Conclusions: The study showed that FNAC and TFT profile both are essential for the proper management of thyroid lesions. FNAC along with hormonal analysis helps in proper patient assessment and management. J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 17-22

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Section: Resultssupporting

confidence: 92%

Evaluation of Different Thyroid Lesions with Fine Needle Aspiration Cytology and Thyroid Function Tests

Ranabhat

Parajuli

Poudel

et al. 2018

J. Gandaki Med. Coll. Nepal

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“…Compared to present study, Poudel et al reported the age of patients in 14 to 70 years range and mean age as 38.8 years. 27 Similar to present study, in their study too, majority of patients (61.5%) were ≤40 years of age. Siddegowda et al on the other hand reported the age range of patients as 11 to 80 years but found most of the cases (56.0%) in age range 21-40 years itself.…”

Section: Discussionsupporting

confidence: 87%

Clinicopathological study of asymptomatic thyroid swelling and its correlation with thyroid function tests

Bhargava

Faiz

Shakeel

et al. 2019

Int J Otorhinolaryngol Head Neck Surg

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Background: Thyroid swelling without symptomatic manifestation is common occurrence and could affect 5 to 20% patients in endemic areas. Majority of them are non neoplastic and may not require surgery. Less than 5% of thyroid nodules are malignant.Methods: Present study was conducted to correlate clinical findings, HRUSG findings, thyroid profile and FNAC findings in patients of asymptomatic thyroid swelling. Results: Proportion of euthyroid patients was higher compared to hyperthyroid and hypothyroid diagnosed as colloid goiter on FNAC findings (82.4% vs. 0.0% and 12.9%). Proportion of hypothyroid was higher compared to euthyroid and hyperthyroid diagnosed as Follicular adenoma (3.2% vs. 0.0% and 1.2%) and colloid goiter with cystic changes (48.4% vs. 0.0% and 10.6%). Proportion of hyperthyroid compared to hypothyroid and euthyroid patients were higher diagnosed as thyroiditis (75.0% vs. 32.3% and 5.9%) and papillary/medullary CA (25.0% vs. 3.2 and 0.0%). A statistically significant association of FNAC diagnosis and thyroid profile of patients with asymptomatic thyroid swelling was found.Conclusions: The present study showed that thyroid dysfunction could play a significant role in determining the underlying pathology behind thyroid swelling and must be evaluated at the earliest using thyroid function tests as the first line of diagnostic tool. In case of suspected thyroid profile; USG neck and FNAC should be done. In view of lack of studies correlating thyroid and clinicopathological profiles of thyroid swellings, further studies to potentiate the present study findings are recommended.

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“…In the present study most common affected age group was fifth decade i.e. 41-50, whereas in other studies like Suman et al, [13], Leonard et al, [14], Silverman et al, [15] and Patel et al, [16] most common age group affected ranged from 20-50 years. Nodular goiter as most common nonneoplastic lesion with 33.75% similar to studies done by Sood et al, [18] and Mahar et al, [17] and most common neoplastic lesion as papillary thyroid carcinoma with 18.75% similar to studies done by Mahar et al, [17], Sood et al, [18] and Jayaram et al, [19].…”

Section: Discussioncontrasting

confidence: 56%

Role of Fine Needle Aspiration Cytology (FNAC) in Surgical Intervention of Thyroid Lesions: in Correlation with Thyroid Hormone Profile

Swetha¹,

Kaza²,

Bhavani³

2021

Middle East Res J Microbiol Biotechnol

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Background: Fine needle aspiration cytology (FNAC) of the Thyroid is over half a century old and has been shown to be superior to clinical, radionucleotide or thyroid ultrasound assessment alone. It is the most accurate, cost-effective, and simplest screening test for rapid diagnosis of thyroid nodules. Evaluation of both cytomorphological pattern and thyroid hormone profile aids in early detection of various thyroid diseases there by reducing surgical intervention. Aims and Objectives: To correlate role of thyroid hormone profile (T3, T4 and TSH) with cytology results, in various thyroid disorders like diffuse nontoxic goiter, diagnosis of solitary/dominant thyroid nodule and thyroid malignancy. To evaluate the clinical correlation with Euthyroid, Hypo and Hyperthyroid picture in various disorders. To calculate the percentage of surgical intervention for various thyroid disorders in view of thyroid profile in correlation with FNAC findings. Material and methods: All patients who underwent thyroid FNAC from July 2017 to June 2018 have been included in the study only if Thyroid profile has been done. The various lesions have been categorised as Euthyroid, Hypothyroid and Hyperthyroid as per the hormone analysis results. The FNAC findings have been reported as per the Bethesda System and classified as per the latest WHO guidelines. Results: predominantly affected gender was females (91.25%), most common affected age group was 41-50 years (30%), 88.75% were euthyroid patients, most common benign lesion on FNAC was nodular goiter (33.75%), malignant lesion was papillary thyroid carcinoma (18.75%), thyroid profile in various thyroid lesions were euthyroid.

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Cytopathological Evaluation of Thyroid by Fine Needle Aspiration Cytology and Correlation with T3 T4 and TSH Levels

Cited by 5 publications

References 0 publications

Evaluation of Different Thyroid Lesions with Fine Needle Aspiration Cytology and Thyroid Function Tests

Evaluation of Different Thyroid Lesions with Fine Needle Aspiration Cytology and Thyroid Function Tests

Clinicopathological study of asymptomatic thyroid swelling and its correlation with thyroid function tests

Role of Fine Needle Aspiration Cytology (FNAC) in Surgical Intervention of Thyroid Lesions: in Correlation with Thyroid Hormone Profile

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