Introduction: Fine needle aspiration cytology (FNAC) is the important part of triple assessment in diagnosing the palpable breast lump. It categorizes the lesion into benign, malignant and its subtypes. It can also identify the residual diseases after treatment.
Introduction: Swelling of the thyroid gland is a commonly encountered clinical problem in all age groups whether benign or malignant. Fine Needle Aspiration Cytology (FNAC) of the thyroid lesions along with hormonal function test helps in the proper preoperative assessment. Ultimately it changes clinical management and improves the patient outcome.Objectives: To describe the cytomorphological features of palpable thyroid nodules using fine needle aspiration cytology (FNAC) along with the assessment of thyroid hormonal status of the patient.Methods: The study was conducted in the Department of Pathology of Gandaki Medical College and Teaching hospital from January 2017 to December 2017 and included 50 patients with thyroid lesions. Cytological assessment was done using FNAC along with serological assessment of thyroid hormones.Results: In the study 50 cases of thyroid swelling were included and evaluated by cytological and hormonal analysis which comprises of 10% males and 90% females with a with a female to male ratio of 9 : 1. Maximum number of cases was seen in the age range 41 - 60 years (46%), mean age being 44.6 years. The cytological diagnosis comprised colloid goiter (58%), lymphocytic thyroiditis (16%), Hashimoto thyroiditis (10%). Thyroid hormone analysis showed 66% euthyroid, 22% hypothyroid and 12% hyperthyroid.Conclusions: The study showed that FNAC and TFT profile both are essential for the proper management of thyroid lesions. FNAC along with hormonal analysis helps in proper patient assessment and management. J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 17-22
Objective: To study the spectrum of histopathological diagnosis of endometrial lesions and their distribution according to age. Methods: All the endometrium samples obtained by the procedure of dilatation and curettage and hysterectomy sent for histopathological examination at Pathology Department of Gandaki Medical College Teaching Hospital, Pokhara, Nepal. The study duration was total 12 months ranging from July 2016 to June 2017. All the endometrial samples were processed, sectioned at 4 - 6 μm and stained with routine H & E stain. Patient’s data including age, sex, procedure of the biopsy taken and histopathological diagnosis were noted. A pathologist, using Olympus microscope, reported the slides. Cases were reviewed by a second pathologist whenever necessary. Results: A total of 128 cases were studied. The most common histopathological diagnosis was proliferative endometrium (28.9%) followed by disorder proliferative endometrium (15.65%). Most of the patients were in age group 36 - 45 years comprising 32.03%. Hydatidiform mole comprised of 7.03% and among Hydatidiform mole, partial mole was more common. Dilatation and curettage (82.8%) was the common procedure in compare to hysterectomy for the evaluation of endometrial lesions. Conclusions: In this study, we observed a variety of endometrial lesions. Most of them are benign; among benign, proliferative endometrium was the common histopathological diagnosis followed by disorder proliferative endometrium. Most common presenting age group was found to be at 36 - 45 years. In evaluation of hydatidiform mole, partial mole was more frequent in compare to complete mole. Conventional dilatation and curettage is the preferred method in developing countries with limited resource to screen endometrial lesion and therefore biopsy should be sent for histopathological examination. Thus histopathological examination of routinely stained hematoxylin and eosin is readily available and widely accepted standard technique for evaluation of the endometrial lesions.
Journal of Political Science Vol.1(1) 1998 p.92-100
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