Cytolysis in normal and complicated pregnancy

Bercovici, B; Schechter, Alexander

doi:10.1016/0002-9378(73)91017-x

Cited by 6 publications

(2 citation statements)

References 6 publications

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“…Even though cytolysis has been proposed by almost all the authors as one of the main features, wet mount of women with trichomonas infection and a few uninfected women have also shown this feature. [ 10 11 ] In our case, the patient had cyclical vaginal discharge, dyspareunia, and localized pruritus. The pH was acidic, and there was a lack of inflammatory infiltrate with overgrowth of lactobacilli, giving the appearance of false clue cells (lactobacilli covering the squamous epithelium).…”

mentioning

confidence: 68%

Vaginal Discharge that Persisted for 6 Years

Mani,

Agarwal,

Raut

et al. 2024

Indian Dermatology Online Journal

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mentioning

confidence: 68%

Vaginal Discharge that Persisted for 6 Years

Mani,

Agarwal,

Raut

et al. 2024

Indian Dermatology Online Journal

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“…However, these studies have, on average, a moderate risk of bias and there are few such studies, so it is difficult to make any inferences. There was an additional prospective cohort study on pregnancy outcomes of 2453 women by Bercovici et al [ 84 ] in 1973 that found cytolysis increased from first to second to third trimester before decreasing prior to delivery; the incidence of cytolysis was significantly higher in women with hyperemesis gravidarum and diabetes and did not appear to have any adverse fetal outcomes. However, the study did not consider the quantity of lactobacilli [ 84 ].…”

Section: Discussionmentioning

confidence: 99%

Scoping review of cytolytic vaginosis literature

Kraut

Carvallo²,

Golonka³

et al. 2023

PLoS ONE

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Background Cytolytic vaginosis (CV) is a little-known, controversial condition that is typically not considered for women presenting with vulvovaginitis symptoms. Objective: The objective of this scoping review was to identify and compile the global evidence on CV. Methods A medical librarian searched Prospero, Wiley Cochrane Library, Ovid Embase, Ovid Medline, EBSCO CINAHL, ProQuest Dissertations and Theses Global, and Scopus, from inception to April 4, 2019 and updated to October 17, 2021. Studies were eligible if they discussed CV. Two independent reviewers conducted study selection and data extraction. Results Sixty-four studies were identified, with 67% of studies (n = 43) published since 2007. Studies were from around the world, including the United States (28%, n = 18), Brazil (11%, n = 7), Portugal (11%, n = 7), and China (11%, n = 7). Fifty percent of studies (n = 32) were reviews; the remainder were observational; and of these, 78% (n = 25) were cross-sectional. The most frequent topics included: diagnosis (19%, n = 12), prevalence (17%, n = 11), and overview of CV (50%, n = 32). Evidence for prevalence in symptomatic women (median prevalence of 5%, interquartile range 3%-8%) was based only on 16% of studies (n = 10) with minimal evidence on prevalence in asymptomatic women and across different geographic regions. Microbiological findings, including abundant lactobacilli and fragmented epithelial cells, were found useful to distinguish between CV and vulvovaginal candidiasis, and Lactobacillus crispatus was noted to dominate the vaginal flora in women with CV. Most studies used subjective criteria to diagnose CV as the condition lacks gold-standard microscopic criteria. The suggested primary treatment (baking soda irrigations) was largely based on expert opinion, and there was minimal evidence on associations between CV and other conditions. Conclusion Knowledge gaps currently exist in all realms of CV research. Additional research is needed to confirm the validity of CV and ensure that women are diagnosed and treated effectively.

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Hormonal Cytopathology of the Vagina

Blair

1987

Gynecologic Endocrinology

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Cytolysis in normal and complicated pregnancy

Cited by 6 publications

References 6 publications

Vaginal Discharge that Persisted for 6 Years

Vaginal Discharge that Persisted for 6 Years

Scoping review of cytolytic vaginosis literature

Hormonal Cytopathology of the Vagina

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