Cytological study of body fluids for malignancy

Saba, Husain; Prakash, Chandra; P.S, Sharmila; Vinitra., K.

doi:10.17511/jopm.2019.i01.08

Cited by 3 publications

(5 citation statements)

References 9 publications

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“…This finding may be due to inclusion of increased number of pediatric population in their study. Most of the patients in our study were in the age group of 0-10 years which is similar to the findings of Saba et al 12 and Bhagat et al 13 Seventeen (85%) out of 20 cases were transudate in nature and three cases were exudate. All three cases were malignant (15%); two cases were from ALL and one case was from medulloblastoma.…”

Section: Discussionsupporting

confidence: 91%

“…16 CSF remained the third most common fluid in many of the studies. 4,7,[12][13][14][15] This corroborates with our finding; CSF being the third most common fluid (4.8%). Shulbha et al 10 in their study on cytology of body fluids found a relatively higher percentage of CSF samples (25.9%) in their study which was even more than pleural fluid (24.1%).…”

Section: Discussionsupporting

confidence: 90%

“…The age range in most of the other studies were from first to ninth decade which was in concordance to our study. [4][5][6][7]9,10,[12][13][14][15] Male preponderance was found in most of the studies 4,5,7-10,12-14 except studies by Ayyagari S et al 6 and Gupta R et al 15 who found female preponderance similar to the present study.…”

Section: Discussionsupporting

confidence: 78%

“…The present study correlated with the findings of Chakrabarti et al, 8 Shulbha et al, 10 Bhagat et al, 13 Bhade et al 14 and Gupta et al 15 Other authors found pleural fluid as the commonest fluid. [4][5][6][7]9,12 This could be attributed to the various epidemiological factors. In our study the difference may be due to more number of cases of abdominal malignancies.…”

Section: Discussionmentioning

confidence: 99%

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Exfoliative cytology of different body fluids- an important aid to primary diagnosis

Tiwari¹,

Thakur²,

Chandrakar³

et al. 2021

IJPO

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Background: Cytological examination of exfoliated cells in various effusion fluids is very challenging and of paramount importance for early diagnosis and management of various pathological processes. It is of utmost significance in identifying malignant cells and hence throws light on the cause, staging and prognosis of cancer. Aims and Objectives: This study was carried out to know the different trends of various types of effusions for various pathological processes with an emphasis on malignant effusion in a tertiary care centre. Materials and Methods: Retrospective, analytical, observational study done over a period of one year from January 2019 to December 2019. A total of 418 cases including peritoneal and pleural and cerebrospinal fluid and urine were analyzed. Samples were centrifuged for five minutes at 2000 rpm and smears prepared from deposit were stained by Papanicolaou (PAP) and May-Grunwald-Giemsa (MGG) stains. Results: Out of 418, 221 were peritoneal effusions, 172 were pleural, 20 cerebrospinal fluids and 5 urine. Out of 221 cases of peritoneal effusions, 144 were non neoplastic and 61 were malignant effusion. Out of total 172 pleural effusions 139 were non neoplastic and 27 neoplastic. Commonest malignancy in peritoneal and pleural fluid was adenocarcinoma from ovary and lung respectively. Conclusions: Cytological evaluation of various fluids is simple, rapid, inexpensive and less invasive tool with high accuracy and thereby reducing the need for invasive investigations. It is especially helpful in evaluating and staging malignancies thereby guiding the clinician in further management.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 78%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Exfoliative cytology of different body fluids- an important aid to primary diagnosis

Tiwari¹,

Thakur²,

Chandrakar³

et al. 2021

IJPO

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“…7 Analisis efusi pleura dengan penilaian sitologi merupakan bagian fundamental dari pemeriksaan efusi pleura. 8 Di Eropa dan Amerika Utara, salah satu penyebab tersering adalah pleura keganasan primer atau sekunder. Dengan mengidentifikasi keganasan dari sitologi efusi pleura dapat menghindarkan pasien dari tindakan yang lebih invasif, investigasi, mengurangi biaya perawatan kesehatan, penting untuk penentuan stadium, dan memungkinkan pemberian pengobatan lebih dini.…”

Section: Pendahuluanunclassified

Profil Sitologi Efusi Pleura di RSUD Zainoel Abidin Banda Aceh

Ismida

Yanti²,

Husna³

et al. 2021

JKS

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Efusi pleura merupakan problem diagnosticutama pada kelainanparukarena pleura merupakansuaturongga yang melapisiparutanpaadaaksesapapun. Analisissitologiefusi pleura seringkalidigunakansebagailinipertamapenapisandalampenegakan diagnosis dan tindakanpenatalaksananlebihlanjut. Pemeriksaansitologiefusi pleura sangatpentingkarenadapatmemberikaninformasiinflamasi, keganasan dan metastasis.Penelitianinimenggunakanmetodedeskriptif, mengamatiseluruhbahanefusi pleura yang dilakukananalisissitologiselamaperiodeduatahun dan diperoleh 697 kasusefusi pleura di laboratoriumPatologiAnatomiRumahSakitZainoelAbidin, Banda Aceh. Hasil pemeriksaansitologi 697 bahanefusi pleura ditemukan paling banyakmenunjukkan diagnosis klinistidakdapatdisimpulkan 344 efusi pleura dan diagnosis klinisbukansuatu proses keganasan 294 (total 91,52%), diantaranya paling banyakmenunjukkansuatuperadangankronisdengansebaransellimfosit yang dominanyaitu 124 (41.5%). Dan dari 59 bahanefusi pleura denganjeniskeganasanmenunjukkanbahwa paling banyakditemukan adenocarsinomayaitu 29 (49,1%) dan terdapat 22 (37,3%) bahanefusi pleura denganjeniskeganasan primer yaituSquamousCellCarsinoma. Sitologiefusi pleura merupakanmodalitasdiagnosticmudah dan sederhana yang sangatmembantudalammenegakkan diagnosis efusi pleura dan berperandalammelakukaneksplorasietiologi dan prognosis penyakit. Oleh karenaitu, semuakelainanefusi pleura yang belumterdiagnosissebaiknyadilakukanpemeriksaansitologiuntuk diagnosis awal dan manajemenpasienselanjutnya.

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Cytomorphological analysis of effusion fluids for detection of malignant cells in a tertiary care hospital in northern India

Sharma,

Asotra,

Asotra

2023

Journal of Cancer Research and Therapeutics

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S Introduction: All body cavities are lined by monolayered mesothelial cells and contain a minimal amount of fluid for lubrication and for protecting the underlying viscera. The peritoneal, pleural, cerebrospinal, sputum, urine, and pericardial fluids comprise the major chunk of body fluids. Material and Methods: The study was conducted in the Department of Pathology of a tertiary care hospital in northern India, over a period of 1 year, from January 2021 to December 2021. A total of 241 samples were included in the study. Results: Out of the 241 samples studied, 99 were peritoneal fluid, 94 were pleural fluids, 29 were CSF, and 18 were sputum samples. Maximum number of patients affected were in the age group of 41–50 years. Female preponderance was seen with male to female ratio of 1:1.7. A total of 143/241 cases (59.33%) were of transudative nature and 98/241 (27.8%) cases were exudative. Out of 241 cases, 43 (17.84%) were neoplastic, 190 (78.83%) were non-neoplastic, four (1.65%) were suspicious for malignancy, and four (1.65%) were where no opinion was possible. Peritoneal fluid was the most frequently encountered fluid accounting for 99 cases (41.07%). Adenocarcinoma was the most common malignancy accounting for 29 cases (67.44%) out of 43 malignant effusions in the present study. Conclusion: Cytological evaluation of body fluids is of significant utility in diagnostic medicine as it allows us to distinguish between benign and malignant etiologies and at the same time offers rapid diagnosis and staging of metastatic disease.

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Cytological study of body fluids for malignancy

Cited by 3 publications

References 9 publications

Exfoliative cytology of different body fluids- an important aid to primary diagnosis

Exfoliative cytology of different body fluids- an important aid to primary diagnosis

Profil Sitologi Efusi Pleura di RSUD Zainoel Abidin Banda Aceh

Cytomorphological analysis of effusion fluids for detection of malignant cells in a tertiary care hospital in northern India

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