No abstract

Confidence in managing human monkeypox cases in Asia: A cross-sectional survey among general practitioners in Indonesia, Acta Tropica (2020),

No abstract

Background: Although there is no licensed vaccine for monkeypox, smallpox vaccine has been shown to be 85% effective in preventing the monkeypox. This study was conducted to assess the willingness of frontline healthcare providers to be vaccinated with smallpox vaccine to prevent monkeypox. Methods: A cross-sectional study was conducted in Indonesia. The willingness was assessed under two scenarios: fully subsidized and non-subsidized vaccine. Explanatory variables such as sociodemographic profile, workplace and professional characteristics, and knowledge of monkeypox were collected. A logistic regression assessed the influence of these explanatory variables on participants' willingness. Results: Out of 510 received participants' responses, 407 (79.8%) were analyzed. With a fully subsidized vaccine scenario, 381 (93.6%) of the participants were willing to be vaccinated and in an unadjusted analysis, gender, education, monthly income, and type of workplace were associated with willingness. With a non-subsidized vaccine (i.e. the vaccine price was US$ 17.9), the proportion who were willing to be vaccinated decreased to 71.9%. In adjusted analyses for both scenarios, gender was the only independent predictor for willingness; men

Bakteri Staphylococcus merupakan salah satu bakteri yang sering menimbulkan infeksi pada manusia.Beberapa spesiesnya merupakan flora normal pada kulit dan selaput lendir manusia, ada yang bersifat patogen yang dapat menyebabkan infeksi piogenik bahkan septikemia. Staphylococcus aureus merupakan spesies yang paling invasif. Bakteri ini memiliki beragam faktor virulensi, yang mencakup protein-protein permukaan yang berperan dalam perlekatan kuman, enzim-enzim yang menguraikan protein, dan toksin yang merusak sel penjamu. Faktor virulensi S. aureus saling mempengaruhi, dengan struktur dan sekresi produknya yang berperan dalam patogenesis infeksi. Banyak faktor yang berperan dalam patogenitas bakteri Staphylococcus aureus, mulai dari metabolit bakteri, faktor virulensi sampai perananprotein adhesi matriks ekstraseluler.