Cyclization of chalcone enables ratiometric fluorescence determination of hydrazine with a high selectivity

Recently, the design, synthesis and development of chemodosimeters for hydrazine with high selectivity and sensitivity has attracted tremendous attention due to its major contributions to human health and disease including applications in various platforms. In this review, we recapitulate different strategies for the design of reaction‐based colorimetric and fluorometric probes for the detection of hydrazine and their applications in hydrazine sensing in living systems. The sensing strategies for hydrazine have been divided into six categories: (a) cleavage of the acetoxy group; (b) the nucleophilic addition‐elimination on keto ester; (c) the nucleophilic substitution‐elimination to tandem cyclization on halo‐ester; (d) the nucleophilic addition reaction to phthalimide derivative to phthalhydrazide; (e) the chemical displacement of active methylene compound to hydrazone derivative and (f) Other different approaches. Additionally, a variety of techniques have been devised here for the detection of hydrazine over other comparable ions and neutral amines.

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“…Wang et al . have synthesized chalcone‐based probe 69 which in presence of hydrazine form highly fluorescent pyrazole derivatives 69 (Figure ).…”

Section: Introductionmentioning

confidence: 99%

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

Manna¹,

Gangopadhyay

Maiti

et al. 2019

ChemistrySelect

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“…These structures are commonly prepared by systematic chemical modifications via condensation using polyaromatic aldehyde and required substituted acetophenone or vice versa [21,22]. The addition of a polyaromatic scaffold into chalcone compounds can bring about significant improvement in their physical properties such as absorption, fluorescence, and beneficial sensing capacity against cations, anions, or some molecules [23][24][25]. It is believed that these improved performances depend on the chemical unification of these electronically specific groups in the chalcone structure.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterisation of Polyaromatic Chalcones with Electron Donation

Atahan

2020

Sakarya University Journal of Science

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In this study, a series of chalcone derivatives was successfully synthesized via condensation of 1acetylpyrene with dimethylamine, diphenylamine or carbazole containing benzaldehyde derivatives at basic conditions. Spectral characterisations were acquired by 1 and 2 dimensional NMR techniques and FTIR. In addition, UV-vis and thermal analysis studies were performed to determine their absorption properties and thermal behaviours, respectively. Lastly, surface and film generation properties were investigated by the means of SEM images on ITO glass to determine usability potential in organic electronics.

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“…2,3 Since N2H4 is water soluble and is widely used, it exists widely in water, which results in widespread pollution. 4,5 More importantly, N2H4 is a highly toxic compound. Direct contact with N2H4 may cause serious damage to the eyes, skin and kidneys, and can damage the digestive, central nervous and circulatory systems.…”

Section: Introductionmentioning

confidence: 99%

A Natural Light Visible Colorimetric Responses Fluorescent Probe for Hydrazine Detection

Yang

et al. 2019

ANAL. SCI.

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A natural light visible colorimetric responses fluorescent probe (Probe 1) was developed for N2H4 detection. The recognition mechanism of Probe 1 for hydrazine is based on addition-cyclization. The LOD of Probe 1 for N2H4 was 80.3 nM (0.0026 mg/L), which is below the national limited standard (0.02 mg/L). When various concentrations of N2H4 were added, the color of the Probe 1 solution was graded gradually from yellow to colorless, which could be observed under natural light. The changing course only takes 5 min. Furthermore, Probe 1 was successful applied to detect N2H4 in mineral water, seawater, tap water and river water. The obtained recovery ranged from 91.91-100.00%. Probe 1 has great potential, developed as a visual tool for N2H4 rapid detection.

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Cyclization of chalcone enables ratiometric fluorescence determination of hydrazine with a high selectivity

Cited by 75 publications

References 53 publications

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

Synthesis and Characterisation of Polyaromatic Chalcones with Electron Donation

A Natural Light Visible Colorimetric Responses Fluorescent Probe for Hydrazine Detection

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