CyberKnife: review of first 1,000 cases at a dedicated therapy center

Muacevic, Alexander; Wowra, Berndt; Reiser, Maximilian

doi:10.1007/s11548-008-0246-1

Cited by 4 publications

(4 citation statements)

References 30 publications

(41 reference statements)

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“…It consists of a 6-DOF computer-controlled manipulator and a dedicated X-ray image-guidance system. This system has a wide range of applications in different clinical areas including surgeries on spine, pediatric, prostate, pancreas, kidney, and lung [46].…”

Section: External Surgical Robotic Systemsmentioning

confidence: 99%

Evolutions and Future Directions of Surgical Robotics: A Review

Najarian

Afshari²

2012

IJCM

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Although the robotics firstly appeared as an entertainment form, its capabilities have continuously advanced from the world’s first industrial robot to the surgical robotic systems which are today capable of performing many surgical maneuvers unaided. However, these surgical robots are not autonomous systems; they are designed to complete a surgeon’s abilities and converting surgeon’s movements into incredibly steady and accurate robotic movements that finally manipulate surgical instruments to assist delicate operations. This novel type of surgery is carried out in the form of minimally invasive surgical procedure and has offered valuable alternatives to enhance traditional open surgery approach. Although the surgical robotic systems began as external robots, technological progresses are directing the surgical robotic systems to endoluminal robots which consist of doing surgical maneuvers by navigating of robot through lumens of human body. Here, we will briefly review different applications of robotic systems in various fields of medicine. Then, we will discuss minimally invasive surgical systems and their role in progressing of minimally invasive surgery as a modern surgery method. By thoroughly investigating a considerable amount of published materials about the minimally invasive surgical technologies, we will study the recent research activities and commercially available samples of surgical robotic systems

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Section: External Surgical Robotic Systemsmentioning

confidence: 99%

Evolutions and Future Directions of Surgical Robotics: A Review

Najarian

Afshari²

2012

IJCM

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“…This is where the optimal selection of patients needs to come to the fore. SBRT will not be suitable for all patients and treatment options should be considered in the multidisciplinary format 8 …”

Section: Introductionmentioning

confidence: 99%

“…SBRT will not be suitable for all patients and treatment options should be considered in the multidisciplinary format. 8 In this review, the author chose to critically examine CK SBRT patient selection for two of the most common sites, the spine and pancreas in the hope of contributing to the research base in this area.…”

Section: Introductionmentioning

confidence: 99%

What type of patients with lesions of the pancreas and spine are suitable candidates for treatment with the CyberKnife robotic radiosurgical system?

McCaighy

2013

J Radiother Pract

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Materials & methodsA systematic literature review was conducted to critically examine patient selection for patients undergoing stereotactic body radiotherapy (SBRT) to the spine and pancreas on the CyberKnife robotic radiosurgical system (CK). Online databases were searched and data was collected and ranked using a system from the Scottish Intercollegiate Guideline Network. The quality of the evidence analysed was insufficient to generate universal recommendations. However, the conclusions reached do help to demonstrate the safety and efficacy of CK treatment to both pancreatic and spinal patients.ResultsExcellent local control rates and minimal acute toxicity were reported within the spinal literature with uncertainties remaining with regard to the precise tolerance of the spinal cord and the reliability of current toxicity prediction methods. For pancreatic patients prognosis remains dismal due to the tendency for patients to present with advanced or inoperable disease. Combinations of CK SBRT and Gemcitabine chemotherapy are given though regimes vary and overall survival is not extended due to the rapid onset of distant metastases. New chemotherapy agents are required as well as better means of predicting response to treatment.ConclusionNo randomised controlled trials or meta-analyses were identified in the review and these are required in order to generate universal guidelines

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“…Radiotherapy and thermotherapy, which are noninvasive, hence have become popular for liver tumor treatment options in recent years. [7][8][9][10][11][12][13] Most of nonsurgical treatment options have to overcome the issues of localizing tumors and avoiding respiration effect on the liver movement.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of external respiratory surrogates for in vivo liver motion estimation

Chang¹,

Ho²,

Yeh³

et al. 2012

Medical Physics

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Purpose: Due to low frame rate of MRI and high radiation damage from fluoroscopy and CT, liver motion estimation using external respiratory surrogate signals seems to be a better approach to track liver motion in real-time for liver tumor treatments in radiotherapy and thermotherapy. This work proposes a liver motion estimation method based on external respiratory surrogate signals. Animal experiments are also conducted to investigate related issues, such as the sensor arrangement, multisensor fusion, and the effective time period. Methods: Liver motion and abdominal motion are both induced by respiration and are proved to be highly correlated. Contrary to the difficult direct measurement of the liver motion, the abdominal motion can be easily accessed. Based on this idea, our study is split into the model-fitting stage and the motion estimation stage. In the first stage, the correlation between the surrogates and the liver motion is studied and established via linear regression method. In the second stage, the liver motion is estimated by the surrogate signals with the correlation model. Animal experiments on cases of single surrogate signal, multisurrogate signals, and long-term surrogate signals are conducted and discussed to verify the practical use of this approach. Results:The results show that the best single sensor location is at the middle of the upper abdomen, while multisurrogate models are generally better than the single ones. The estimation error is reduced from 0.6 mm for the single surrogate models to 0.4 mm for the multisurrogate models. The long-term validity of the estimation models is quite satisfactory within the period of 10 min with the estimation error less than 1.4 mm. Conclusions: External respiratory surrogate signals from the abdomen motion produces good performance for liver motion estimation in real-time. Multisurrogate signals enhance estimation accuracy, and the estimation model can maintain its accuracy for at least 10 min. This approach can be used in practical applications such as the liver tumor treatment in radiotherapy and thermotherapy.

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CyberKnife: review of first 1,000 cases at a dedicated therapy center

Cited by 4 publications

References 30 publications

Evolutions and Future Directions of Surgical Robotics: A Review

Evolutions and Future Directions of Surgical Robotics: A Review

What type of patients with lesions of the pancreas and spine are suitable candidates for treatment with the CyberKnife robotic radiosurgical system?

Effectiveness of external respiratory surrogates for in vivo liver motion estimation

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