Cutaneous metastasis to the scalp from squamous cell carcinoma of the cervix

Park, J. Y.; Lee, Hoi-Seon; Cho, K. H.

doi:10.1046/j.1365-2230.2003.01128.x

Cited by 19 publications

(27 citation statements)

References 9 publications

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“…The lesions may appear as multiple dermal and subcutaneous nodules on the chest, back, abdomen, lower extremity, axilla, neck and scalp. The nodules are usually firm, tender and non‐ulcerative 114,130,166 . Metastases from the endometrial carcinoma usually appear as multiple pruritic skin nodules on the lower abdomen, groin or the upper thigh.…”

Section: Skin Metastases Of Carcinomasmentioning

confidence: 99%

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Skin metastasis: a pathologist's perspective

2010

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Skin metastasis is defined as the spread of malignant cells from a primary malignancy to the skin. It is one manifestation of systemic spread of cancer. The tumor cells originate either from an internal malignancy or from a primary skin cancer. This study presents a literature review concerning these issues as well as this author's experience encountered throughout 19 years of surgical pathology and dermatopathology practice. Several conclusions are evident. Generally, skin metastases are encountered in 0.7-9% of all patients with cancer and as such the skin is an uncommon site of metastatic disease when compared to other organs. There is usually a long-time lag between the diagnosis of the primary malignancy and the recognition of the skin metastases. However, these metastases may be the first indication of the clinically silent visceral malignancies. The regional distribution of the skin metastasis, although not always predictable, is related to the location of the primary malignancy and the mechanism of metastatic spread. The relative frequency of skin metastasis correlates with the type of primary cancer, which occurs in each sex. For instance, lung and breast carcinomas are the most common primaries that send skin metastasis in men and women, respectively. The head and neck region and the anterior chest are the areas of greatest predilection in men. The anterior chest wall and the abdomen are the most commonly involved sites in women. Skin metastases usually appear as non-specific groups of discrete firm painless nodules that emerge rapidly without any explanation. They vary in size from so tiny as to be of 'miliary lesions' to as large as 'Hen's egg size'. Some skin metastasis may mimic specific dermatological conditions such as cutaneous cyst, dermatofibroma, pyogenic granuloma, hemangioma, papular eruptions, herpes zoster eruptions, rapidly infiltrating plaques, alopecic patches, cellulitis and erysipelas. Histologically, the skin metastases usually show features reminiscent of the primary malignancy, but with variable degrees of differentiation. Molecularly, skin metastasis is an organized, non-random and organ-selective process orchestrated by interaction among several heterogeneous molecules, which are largely unknown. Metastasis to the skin is often a pre-terminal event that heralds poor outcome.

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Section: Skin Metastases Of Carcinomasmentioning

confidence: 99%

“…The nodules are usually firm, tender and nonulcerative. 114,130,166 Metastases from the endometrial carcinoma usually appear as multiple pruritic skin nodules on the lower abdomen, groin or the upper thigh. A biopsy of the skin lesions usually shows histological features similar to the primary tumor.…”

Section: Meningiomamentioning

confidence: 99%

Skin metastasis: a pathologist's perspective

2010

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“…In females, the most frequent sources of the skin metastases are carcinomas of breast (most common primary origin), colon, ovaries, and lungs as well as melanomas. Other studies include renal cell, uterine cervix [8, 9], and gastrointestinal cancer [10–12]. The pattern of metastasis also depends on the age of the patient [6].…”

Section: Discussionmentioning

confidence: 99%

Scalp Metastasis from Leiomyosarcoma of the Inferior Vena Cava Sign as the First Clinical Sign: A Case Report

Muñoz

Masferrer

2012

Case Reports in Oncological Medicine

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The presentation of scalp metastases from leiomyosarcoma of the vena cava is an extremely infrequent event. There are no other publications that describe such finding and very few of leiomyosarcoma in vessels. About this event we have reviewed the English literature describing studies on scalp metastases and skin metastases in general: their incidence, origin, clinical appearance, meaning, and diagnosis. The case we describe would be the second one presented worldwide because, as far as we know, it has been only one more published in 2005.

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“…Cutaneous metastasis of cervical cancer is common at the abdominal wall, vulva, and anterior chest wall2; however, cases presenting at the scalp3,4, extremities5, umbilical surgical scar6,7, and drainage site8 have been reported. Only a few cases have been previously reported in Korean literature (Table 1)9-11.…”

Section: Discussionmentioning

confidence: 99%

Vulval Metastasis from Squamous Cell Carcinoma of the Cervix Clinically Presenting as Lymphangioma Circumscriptum

et al. 2011

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Patients with cervical cancer may develop local recurrence or distant metastasis, and the rate of these events is increased in proportion to the clinical stage. Cutaneous metastasis of cervical cancer is very rare and only a few cases have been reported in Korean literature. It is common at the abdominal wall, vulva, and anterior chest wall and mainly presents as an asymptomatic dermal or subcutaneous nodule, ulcer or plaque. We herein report on an interesting case of vulval metastasis from squamous cell carcinoma of the cervix with an unusual clinical manifestation resembling lymphagioma circumscriptum.

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Cutaneous metastasis to the scalp from squamous cell carcinoma of the cervix

Cited by 19 publications

References 9 publications

Skin metastasis: a pathologist's perspective

Skin metastasis: a pathologist's perspective

Scalp Metastasis from Leiomyosarcoma of the Inferior Vena Cava Sign as the First Clinical Sign: A Case Report

Vulval Metastasis from Squamous Cell Carcinoma of the Cervix Clinically Presenting as Lymphangioma Circumscriptum

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