Cutaneous Lesions of Metastatic Visceral Malignancy Mimicking Pyogenic Granuloma

Hager, C; Cohen, Philip R.

doi:10.3109/07357909909021429

Cited by 37 publications

(16 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…8 One study found that 1% of genitourinary tumors will metastasize to skin, and of those, most are renal cell carcinomas. 6 Another found that the rate of cutaneous metastases from renal cell carcinoma was 3.3%, but this series included a smaller number of cases.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Renal Medullary Carcinoma Metastatic to the Scalp

Johnson

Krauland

Owens

et al. 2011

The American Journal of Dermatopathology

View full text Add to dashboard Cite

A 40-year-old woman presented to the Brooke Army Medical Center Emergency Department complaining of 2 episodes of gross hematuria. Computed tomography and intravenous pyelogram revealed a right renal mass. A radical nephrectomy was performed with complete excision of the mass with negative margins on histological examination. The patient was diagnosed with renal medullary carcinoma, Fuhrman grade 4, based upon histological examination. A positron emission tomography scan revealed no other evidence of the disease. The pathologic stage was stage I renal medullary carcinoma. Four months after her nephrectomy, the patient developed a papule on her right frontal scalp. Initially thought to be a cyst, the papule increased in size over the course of 2 months and eventually ulcerated. At that time, she presented to the Wilford Hall Medical Center Dermatology Clinic with a 2.5-cm ulcerated tumor with pink rolled borders. A punch biopsy of the tumor revealed an infiltrating carcinoma with scattered glandular lumina and desmoplastic and mucinous stroma. The carcinoma was completely intradermal. Expert consultation confirmed the diagnosis of metastatic renal medullary carcinoma. Clear cell (conventional) and papillary renal cell carcinomas are known to metastasize to the skin, including the scalp. Renal medullary carcinoma commonly metastasizes to the regional lymph nodes, lung, liver, or adrenals. To our knowledge, this is the first report of a cutaneous metastasis of renal medullary carcinoma.

show abstract

Section: Discussionmentioning

confidence: 99%

“…To our knowledge, cutaneous metastatic disease has not been reported in renal medullary carcinoma. [6][7][8][9][10][11] Here, we present the first case of renal medullary carcinoma metastatic to the scalp.…”

Section: Introductionmentioning

confidence: 93%

Renal Medullary Carcinoma Metastatic to the Scalp

Johnson

Krauland

Owens

et al. 2011

The American Journal of Dermatopathology

View full text Add to dashboard Cite

show abstract

“…Other diagnoses such as angioma tuft, hemangioma, lobular angioma, micro capillary angioma, Masson tumors, reactional angioendotheliomatosis, angiokeratoma and bacillary angiomatosis [6, 7] could draw our attention in front of this kind of image. These observations prompt us to think directly to bacterial culture and histological examination as key for the diagnosis of this tumor.…”

Section: Discussionmentioning

confidence: 99%

Clinical case of Botryomycome fulminant at the Center of Diagnostic and Treatment of Tuberculosis of Baleng (West - Cameroon)

Noubom

Kenfack²,

Donfack³

et al. 2013

Pan Afr Med J

View full text Add to dashboard Cite

Botryomycome also called pyogenic granuloma, is an inflammatory tumor of the skin and mucous membranes often caused by superinfection of minor traumatism. Its uniqueness lies in its granulomatous organization in which each granulation contains bacteria and the predominance of many newly formed blood vessels, with the lights on variables ratings and a turgid endothelium responsible for the ulcero-hemorragic appearance. This delicate condition poses a real problem of treatment which included: an appropriate antibiotherapy, surgical removal or electrocoagulation which, until today is more difficult in countries with limited income. An octagenarian came to our hospital with a large mass on the left foot. This mass had the appearance of a malignant tumor. However, the anatomopathologic diagnosis showed that it was a pyogenic granuloma. The importance of the mass, its location on the sole of the foot, imposed the functional impairment of this member. Electrocoagulation is not available in our hospital and the surgical excision proposed was refused by the patient. The patient was treated with the antibiotics Ceftriaxone and Gentalline at indicated doses for 15 days. After the failure of that antibiotherapy treatment, as a last resort, the patient was treated for a month with another combination of antibiotics (free of cost) made of dapsone and rifampicin. This new combination gave very good results. This example shows dapsone and rifampicin can be use as a new weapon for the management of pyogenic granuloma in countries with limited incomes.

show abstract

“…[2][3][4][5][6][7][8][9] When affecting the fingers, the distal phalanx of the third finger appears to be the site most commonly affected for reasons that remain to be clarified. [3][4][5][6][7][8] In the present case, the patient had a lytic lesion, with bone absorption affecting almost the entire distal phalanx; however, the affected finger was the fourth rather than the third finger. In addition, there was a skin lesion, albeit without bone involvement, on the fourth finger of the contralateral hand.…”

Section: Discussionmentioning

confidence: 99%

Metástase cutânea rara de provável carcinoma basaloide de cólon simulando granuloma piogênico

Verardino

Silva

Obadia

et al. 2011

An. Bras. Dermatol.

View full text Add to dashboard Cite

Acrometastasis is a rare occurrence, especially when affecting the hands. It represents around 0.007-0.2% of all metastatic lesions. The most common site of origin is the lung, accounting for 40-50% of all cases reported in the literature. Kidneys and breasts are other sites also associated with neoplastic lesions that disseminate to the hands. More rarely, the site of origin may be the gastrointestinal tract or other systemic tumors or sarcomas. Early diagnosis is difficult, since the condition may be asymptomatic or may mimic tenosynovitis, arthritis, paronychia, pyogenic granuloma or a local infection. In the present paper, the authors report on a patient with the diagnosis of acrometastasis on both hands originating from a basaloid carcinoma of the anal canal. Response to radiotherapy was poor. Keywords: Colonic neoplasms; Granuloma, pyogenic; Neoplasm metastasisResumo: As acrometástases, principalmente para as mãos, são incomuns e representam cerca de 0,007-0,2% de todas as lesões metastáticas. O pulmão é o sítio de origem mais comum, colaborando com 40-50% dos casos relatados na literatura. Os rins e mamas são outras localizações também relacionadas a neoplasias que metastatizam para as mãos, além de, mais raramente, trato gastrointestinal, outros tumores sistêmicos e sarcomas. Seu diagnóstico precoce é difícil, pois pode ser assintomático, se assemelhar a tenossinovite, artrite, paroníquia, granuloma piogênico ou infecção local. No presente relato, os autores apresentam paciente com diagnóstico de acrometástase, em ambos os quartos quirodáctilos, oriunda de carcinoma basaloide de canal anal, com pobre resposta à radioterapia.

show abstract

Cutaneous Lesions of Metastatic Visceral Malignancy Mimicking Pyogenic Granuloma

Cited by 37 publications

References 18 publications

Renal Medullary Carcinoma Metastatic to the Scalp

Renal Medullary Carcinoma Metastatic to the Scalp

Clinical case of Botryomycome fulminant at the Center of Diagnostic and Treatment of Tuberculosis of Baleng (West - Cameroon)

Metástase cutânea rara de provável carcinoma basaloide de cólon simulando granuloma piogênico

Contact Info

Product

Resources

About