Current Use of Carbon-Based Materials for Biomedical Applications—A Prospective and Review

With growing interest, a large number of researches have been conducted on carbon-based nanomaterials (CBNs). However, their uses are limited due to comprehensive potential environmental and human health effects. It is often confusing for researchers to make an informed choice regarding the versatile carbon-based nanocarrier system and its potential applications. This review has highlighted emerging applications and cutting-edge progress of CBNs in drug delivery. Some critical factors like enzymatic degradation, surface modification, biological interactions, and bio-corona have been discussed here. These factors will help to fabricate CBNs for effective drug delivery. This review also addresses recent advancements in carbon-based target specific and release controlled drug delivery to improve disease treatment. The scientific community has turned their research efforts into the development of novel production methods of CBNs to make their production more attractive to the industrial sector. Due to the nanosize and diversified physical properties, these CBNs have demonstrated distinct biological interaction. Thus long-term preclinical toxicity study is recommended before finally translating to clinical application.

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“…There are several methods reported to pass the CNTs through cells. They are endocytosis, diffusion, or insertion (Rajakumar et al, 2020).…”

Section: Mechanism Of Drug Targetingmentioning

confidence: 99%

Drug Delivery With Carbon-Based Nanomaterials as Versatile Nanocarriers: Progress and Prospects

Debnath

Srivastava

2021

Front. Nanotechnol.

100

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“…It is also used in gas sensors such as NO 2 , CO, H 2 S, H 2 , NO, NH 3 , and CO 2 [76][77][78][79][80][81][82][83][84][85], or even as a biosensor for the detection of dopamine [86,87], β-nicotinamide adenine dinucleotide [88], paracetamol [87,89], Kojic acid [90], uric acid [86,87], vanillin [91], and caffeic acid [92]. Graphene is also used as a drug carrier [93][94][95][96][97] and as a charge conductor in solar cells as well as a light collector including cells and photodetectors [53,[60][61][62][98][99][100]. He et al [101] prepared a three-dimensional graphene-CNTs@ Se aerogel, usingCNTs/selenium that is sandwiched between graphene nanosheets via an environmentally friendly solvothermal method.…”

Section: Graphite and Graphenementioning

confidence: 99%

Current State of Porous Carbon for Wastewater Treatment

et al. 2020

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Porous materials constitute an attractive research field due to their high specific surfaces; high chemical stabilities; abundant pores; special electrical, optical, thermal, and mechanical properties; and their often higher reactivities. These materials are currently generating a great deal of enthusiasm, and they have been used in large and diverse applications, such as those relating to sensors and biosensors, catalysis and biocatalysis, separation and purification techniques, acoustic and electrical insulation, transport gas or charged species, drug delivery, and electrochemistry. Porous carbons are an important class of porous materials that have grown rapidly in recent years. They have the advantages of a tunable pore structure, good physical and chemical stability, a variable specific surface, and the possibility of easy functionalization. This gives them new properties and allows them to improve their performance for a given application. This review paper intends to understand how porous carbons involve the removal of pollutants from water, e.g., heavy metal ions, dyes, and organic or inorganic molecules. First, a general overview description of the different precursors and the manufacturing methods of porous carbons is illustrated. The second part is devoted to reporting some applications such using porous carbon materials as an adsorbent. It appears that the use of porous materials at different scales for these applications is very promising for wastewater treatment industries.

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“…This is helped by various surface modifications, strict particle size ranges, etc. [ 26 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 ].…”

Section: Introductionmentioning

confidence: 99%

Advances in Drug Delivery Nanosystems Using Graphene-Based Materials and Carbon Nanotubes

Jampílek

Kráľová

2021

Materials

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Carbon is one of the most abundant elements on Earth. In addition to the well-known crystallographic modifications such as graphite and diamond, other allotropic carbon modifications such as graphene-based nanomaterials and carbon nanotubes have recently come to the fore. These carbon nanomaterials can be designed to help deliver or target drugs more efficiently and to innovate therapeutic approaches, especially for cancer treatment, but also for the development of new diagnostic agents for malignancies and are expected to help combine molecular imaging for diagnosis with therapies. This paper summarizes the latest designed drug delivery nanosystems based on graphene, graphene quantum dots, graphene oxide, reduced graphene oxide and carbon nanotubes, mainly for anticancer therapy.

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Current Use of Carbon-Based Materials for Biomedical Applications—A Prospective and Review

Cited by 51 publications

References 95 publications

Drug Delivery With Carbon-Based Nanomaterials as Versatile Nanocarriers: Progress and Prospects

Drug Delivery With Carbon-Based Nanomaterials as Versatile Nanocarriers: Progress and Prospects

Current State of Porous Carbon for Wastewater Treatment

Advances in Drug Delivery Nanosystems Using Graphene-Based Materials and Carbon Nanotubes

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