Current advances in bone tissue engineering concerning ceramic and bioglass scaffolds: A review

Ribas, Renata Guimarães; Schatkoski, Vanessa Modelski; Montanheiro, Thaís Larissa do Amaral; Menezes, Beatriz Rossi Canuto de; Stegemann, C.; Leite, Douglas Marcel Gonçalves; Thim, Gilmar Patrocínio

doi:10.1016/j.ceramint.2019.07.096

Cited by 164 publications

(100 citation statements)

References 93 publications

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“…432 The surface nanoporosity was also found to foster adhesion of cells to biomaterials 433 and bone ingrowth in bioactive glass scaffolds. 434 The most important requirements of fabricating scaffolds for bone tissue engineering that can be capable of inciting the tissue growth are; 62,96,432,[435][436][437] (i) Biocompatibility: the scaffold has to be biocompatible, bioactive and must assist in the attachment, proliferation and cell differentiation in vivo and must not deliver any toxic byproduct or persuade any harmful inammatory reactions.…”

Section: Sol-gel Derived Porous Glasses For Bone Tissue Regenerationmentioning

confidence: 99%

Recent advances and future perspectives of sol–gel derived porous bioactive glasses: a review

et al. 2020

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Section: Sol-gel Derived Porous Glasses For Bone Tissue Regenerationmentioning

confidence: 99%

Recent advances and future perspectives of sol–gel derived porous bioactive glasses: a review

et al. 2020

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“…Recently, cement scaffolds were prepared containing calcium silicate and calcium phosphate. Sequential testing showed that scaffold containing calcium phosphate had a hierarchically porous structure for improvement of bone tissue regeneration [185]. On the other hand, calcium phosphate provided retention of secondary structure and promoted bioactivity of such constructed scaffold.…”

Section: Bone Tissue Engineeringmentioning

confidence: 99%

Nanostructured Materials for Artificial Tissue Replacements

Pryjmaková

Kaimlová

Hubáček

et al. 2020

IJMS

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This paper review current trends in applications of nanomaterials in tissue engineering. Nanomaterials applicable in this area can be divided into two groups: organic and inorganic. Organic nanomaterials are especially used for the preparation of highly porous scaffolds for cell cultivation and are represented by polymeric nanofibers. Inorganic nanomaterials are implemented as they stand or dispersed in matrices promoting their functional properties while preserving high level of biocompatibility. They are used in various forms (e.g., nano- particles, -tubes and -fibers)—and when forming the composites with organic matrices—are able to enhance many resulting properties (biologic, mechanical, electrical and/or antibacterial). For this reason, this contribution points especially to such type of composite nanomaterials. Basic information on classification, properties and application potential of single nanostructures, as well as complex scaffolds suitable for 3D tissues reconstruction is provided. Examples of practical usage of these structures are demonstrated on cartilage, bone, neural, cardiac and skin tissue regeneration and replacements. Nanomaterials open up new ways of treatments in almost all areas of current tissue regeneration, especially in tissue support or cell proliferation and growth. They significantly promote tissue rebuilding by direct replacement of damaged tissues.

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“…In modern medicine, advance is closely related not only to new drugs and treatment methods but also to the development of materials engineered to interact with biological systems. Such materials, called biomaterials, are used primarily in restorative medicine, where they replace the tissues of a living organism as the implants [1]. A modern trend in the engineering of implantable biomaterials is the modification of their surfaces by producing coatings [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Mechanical and Barrier Properties of Al2O3/TiO2/ZrO2 Layers in Oxide–Hydroxyapatite Sandwich Composite Coatings Deposited by Sol–Gel Method on Ti6Al7Nb Alloy

et al. 2020

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In this study, coatings of different oxides (TiO2, Al2O3, ZrO2) and hydroxyapatite (HAp) as well as sandwich composite hydroxyapatite with an oxides sublayer (oxide+HAp) were deposited on Ti6Al7Nb alloy using the sol–gel dip-coating method. The coatings were characterized in terms of morphology (optical microscope), surface topography (AFM), thickness (ellipsometry), and crystal structure (XRD/GIXRD). The mechanical properties of the coatings—hardness, Young’s modulus, and adhesion to the substrate—were examined using nanoindentation and scratch tests. The barrier properties of the coatings against the migration of aluminum ions were examined by measuring their concentration after soaking in Hank’s balanced salt solution (HBSS) with the use of optical emission spectrometry of inductively coupled plasma (ICPOES). It was found that all the oxide and HAp coatings reduced the permeation of Al ions from the Ti6Al7Nb alloy substrate. The best features revealed an Al2O3 layer that had excellent barrier properties and the best adhesion to the substrate. Al2O3 as a sublayer significantly improved the properties of the sandwich composite HAp coating.

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Current advances in bone tissue engineering concerning ceramic and bioglass scaffolds: A review

Cited by 164 publications

References 93 publications

Recent advances and future perspectives of sol–gel derived porous bioactive glasses: a review

Recent advances and future perspectives of sol–gel derived porous bioactive glasses: a review

Nanostructured Materials for Artificial Tissue Replacements

Comparison of Mechanical and Barrier Properties of Al2O3/TiO2/ZrO2 Layers in Oxide–Hydroxyapatite Sandwich Composite Coatings Deposited by Sol–Gel Method on Ti6Al7Nb Alloy

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