CT Features of Renal Cell Carcinoma with Emphasis on Relation to Tumor Size

Zagoria, Ronald J.; Wolfman, Neil T.; Karstaedt, Nolan; Hinn, G; Dyer, Raymond B.; Chen, Yu Men

doi:10.1097/00004424-199003000-00010

Cited by 62 publications

(10 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our study correlates well with studies of Bajwa et al [48] (2007) and Zagoria et al [31] (1990) who concluded that helical CT is highly sensitive in diagnosing and staging of renal masses.…”

supporting

confidence: 92%

Comparative Evaluation of Ultrasonography and Computed Tomography Findings in Renal Masses.

Mohi¹,

Sunita²,

Mittal³

2017

IJAR

View full text Add to dashboard Cite

supporting

confidence: 92%

Comparative Evaluation of Ultrasonography and Computed Tomography Findings in Renal Masses.

Mohi¹,

Sunita²,

Mittal³

2017

IJAR

View full text Add to dashboard Cite

“…The significant attenuation differences may be explained by the vascularization characteristics. Conventional ccRCC is known to display improved vascularization, whereas pRCC is typically a hypovascular mass (17,20). Tumor vascularity can be evaluated in vivo using the enhancement parameters of dynamic CT via the heterogeneity of tumor angiogenesis (21).…”

Section: Discussionmentioning

confidence: 99%

Clear cell renal cell carcinoma and papillary renal cell carcinoma: differentiation of distinct histological types with multiphase CT

Bata

Gyebnar

Tárnoki

et al. 2013

Diagn Interv Radiol

View full text Add to dashboard Cite

ABDOMINAL IMAGINGORIGINAL ARTICLE PURPOSE Conventional clear cell renal cell carcinoma (ccRCC) and papillary renal cell carcinoma (pRCC) have different behavioral characteristics and clinical management strategies (nephrectomy vs. nephron-sparing surgery). Our aim was to retrospectively evaluate the contrast enhancement pattern of ccRCC and pRCC and evaluate its possible diagnostic role for preoperative differentiation using a standardized protocol. MATERIALS AND METHODSQuadriphasic multidetector computed tomography (CT) images (unenhanced, corticomedullary, nephrographic, and excretory phases) of 19 patients with 20 ccRCC and 14 patients with 15 pRCC lesions (mean ages, 62.3±14.1 and 61.4±13.7 years, respectively) were reviewed retrospectively. The attenuation characteristics were compared with the attenuation of the normal renal cortex using either multiple 10 mm 2 regions of interest or whole tumor attenuation measurements. The degree of contrast enhancement was also compared. RESULTSUnivariate analysis revealed that ccRCC lesions showed higher mean attenuation values on the corticomedullary and nephrographic phases compared with pRCC masses (P < 0.05) using both measurement techniques. CONCLUSIONThe findings underscore the importance of multiphase CT in the differentiation of these two subtypes of RCC using standard assessment techniques. The measurement of the degree of enhancement on contrast-enhanced multidetector CT may be a simple and useful method to radiologically differentiate between the two histological types of RCC.

show abstract

“…To our knowledge, however, venous extension of calcified tumor thrombus has not been described. In a series of 215 patients with renal cell carcinoma, discreet calcification was noted in the primary tumor in 24 (31%) [1]. In this series, there were no cases of calcified tumor thrombus extending into the renal vein or IVC.…”

mentioning

confidence: 61%

“…Calcification within the primary tumor and venous extension of tumor are not unusual [1][2][3][4]. To our knowledge, however, venous extension of calcified tumor thrombus has not been described.…”

Section: Discussionmentioning

confidence: 81%

CT appearance of calcified tumor thrombus in the inferior vena cava

1993

View full text Add to dashboard Cite

Abstract.We report the unusual occurrence of calcified tumor thrombus in the inferior vena cava (IVC) in a patient with renal cell carcinoma diagnosed by computed tomography (CT).Key words: Renal cell carcinoma, calcified tumor thrombus--Computed tomography.Extension of tumor thrombus into the inferior vena cava (IVC) is a well-known complication of renal cell carcinoma. The thrombi appear on computed tomography (CT) as solid endoluminal masses with the same attenuation as the primary renal tumor. We report the unusual occurrence of calcified tumor thrombus in the IVC in a patient with renal cell carcinoma who also had calcification of the primary tumor and metastatic lymph nodes. To our knowledge, this is the first report of calcified tumor thrombus in the IVC from renal cell carcinoma. Case ReportA 43-year-old woman was admitted to our institution for treatment of metastatic renal cell carcinoma. She was well until 6 months prior to admission when she noted a left supraclavicular mass. Biopsy of the mass demonstrated adenocarcinoma. CT revealed a right renal neoplasm with metastatic disease in the chest and abdomen. She initially refused treatment.On physical examination there was a 12 x 6 cm fight flank mass, a 2 cm left supraclavicular mass, and bilaterallower extremity edema. Laboratory evaluation was remarkable for a hemoglobin of 9.5 g/ dl, lactate dehydrogenase of 407 IU, and gross blood in the urine.CT of the chest and abdomen demonstrated a partially calcified right renal mass replacing most of the kidney. There was calcified tumor thrombus extending into the right renal vein and proximally (Fig. 1A-C). Calcified lymphadenopathy was noted in the retroperitoneum, mediastinum, and hila (Fig. 1D). Multiple lung metastases were present and there were extensive retroperitoneal and subcutaneous venous collaterals.She was treated with interleukin and no additional imaging procedures were obtained. DiscussionThe CT features of renal cell carcinoma have been thoroughly described. Calcification within the primary tumor and venous extension of tumor are not unusual [1][2][3][4]. To our knowledge, however, venous extension of calcified tumor thrombus has not been described. In a series of 215 patients with renal cell carcinoma, discreet calcification was noted in the primary tumor in 24 (31%) [1]. In this series, there were no cases of calcified tumor thrombus extending into the renal vein or IVC. In another series, which reported the results of CT staging of 100 renal cell carcinomas, no cases of calcified tumor thrombus were described in the 18 patients with venous extension [2].Although calcified tumor thrombus in the renal vein and IVC in patients with renal cell carcinoma is rare, it could be important for persons doing abdominal imaging to be aware of this entity. The diagnosis on CT is straightforward due to the high attenuation of calcium. On ultrasound or magnetic resonance imaging (MRI), however, the presence of calcified tumor thrombus could result in confusion if this possibility was not considered. Ca...

show abstract

CT Features of Renal Cell Carcinoma with Emphasis on Relation to Tumor Size

Cited by 62 publications

References 0 publications

Comparative Evaluation of Ultrasonography and Computed Tomography Findings in Renal Masses.

Comparative Evaluation of Ultrasonography and Computed Tomography Findings in Renal Masses.

Clear cell renal cell carcinoma and papillary renal cell carcinoma: differentiation of distinct histological types with multiphase CT

CT appearance of calcified tumor thrombus in the inferior vena cava

Contact Info

Product

Resources

About