Cryotherapy for HPV clearance in women with biopsy‐confirmed cervical low‐grade squamous intraepithelial lesions

Chumworathayi, Bandit; Thinkhamrop, Jadsada; Blumenthal, Paul D.; Thinkhamrop, Bandit; Pientong, Chamsai; Ekalaksananan, Tipaya

doi:10.1016/j.ijgo.2009.09.012

Cited by 17 publications

(20 citation statements)

References 22 publications

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“…The Low risk genotype was not detected in any samples. In women, about 50% of new infections of most low-grade squamous intraepithelial lesions may disappear spontaneously within 12 months whereas the clearance rate in older women is lower (Chumworathayi et al, 2010). Approximately 1% of low-grade squamous intraepithelial lesions and 12% of high-grade squamous intraepithelial lesions may progress to invasive cervical cancer and more than 90% of HR-HPV genotypes pose an increased risk for progression to cervical cancer.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Human Papillomavirus in Women from Saudi Arabia

Turki¹,

Sait²,

Anfinan³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Background: Human papillomavirus (HPV) infection is the main causes of cervical cancer in women worldwide. The goal of the present study was to determine the prevalence and distribution of HPV genotypes in women from Saudi Arabia. Recently, several HPV detection methods have been developed, each with different sensitivities and specificities. Methods: In this study, total forty cervical samples were subjected to polymerase chain reaction and hybridization to BioFilmChip microarray assessment. Results: Human papillomavirus (HPV) infections were found in 43% of the specimens. The most prevalent genotypes were HPV 16 (30%) HPV 18 (8.0%) followed by type HPV 45, occurring at 5.0%. Conclusion: Our finding showed the HPV infection and prevalence is increasing at alarming rate in women of Saudi Arabia. There was no low risk infection detected in the tested samples. The BioFilmChip microarray detection system is highly accurate and suitable for detection of single and multiple infections, allowing rapid detection with less time-consumption and easier performance as compared with other methods.

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Section: Discussionmentioning

confidence: 99%

Prevalence of Human Papillomavirus in Women from Saudi Arabia

Turki¹,

Sait²,

Anfinan³

et al. 2013

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…In young women, about 50% of new infections of most low-grade squamous intraepithelial lesions may disappear spontaneously within 12 months whereas the clearance rate in older women is lower (Chumworathayi et al, 2010). Approximately 1% of low-grade squamous intraepithelial lesions and 12% of high-grade squamous intraepithelial lesions may progress to invasive cervical cancer and more than 90% of HR-HPV genotypes pose an increased risk for progression to cervical cancer.…”

Section: Discussionmentioning

confidence: 99%

High-risk Human Papillomavirus Genotype Detection by Electrochemical DNA Chip Method

Chansaenroj

Theamboonlers²,

Chinchai³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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According to a cohort study, HPV cumulative incidence rates are associated with younger women, certain ethnic groups and high frequency of alcohol consumption. Forty-three percent of women, who had attended at least one follow-up visit, were HPV negative. The incidence tended to decrease by 20% in the first year, 14% and 9% in the second and third years, respectively. The median duration of HPV infection was 8 months. 70% of women were no longer infected one year after the incident and 9% continued to be infected for two years. The longest median duration of infection was established for HPV 16, 18, 61, 73 and AE7. In developed countries, the highest rates of HPV infection have been observed among 15-25-year old women who might reflect transmission during their first sexual intercourse whereas the infection rate Jira Chansaenroj et al

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“…One of the treatment effects with either cryotherapy or LEEP may be stimulation of the immune response, promoting clearance of HPV after treatment, even if the entire lesion or the entire transformation zone is not excised or ablated, although one small study failed to show an effect of cryotherapy on HPV clearance one year after treatment (Taylor 2010;Chumworathayi et al 2010).…”

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confidence: 99%