Crosslinker effects on swelling and gel properties of pH- and temperature-responsive poly (NIPAM/IA/AM) hydrogels

Wan, Tao; Xiong, Jing; Zhao, Qihua; Wu, Daqing; Tang, Li; Ling, Liming; Chen, Qiaohe

doi:10.1007/s00289-015-1557-3

Cited by 9 publications

(4 citation statements)

References 36 publications

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“…Thermoresponsive particles based on PNIPAM are usually produced by thermal freeradical polymerization of the related monomers. Typically, the formation of particles occurs from an emulsion [12], by precipitation polymerization from a solvent [13], or by growth on preformed nanoparticle seeds [14,15]. The seed-based method can also be used for generating core-multishell particles, which mostly have an inorganic core in the nanometer range [15].…”

Section: Introductionmentioning

confidence: 99%

Microfluidic Synthesis and Properties of Thermoresponsive Hydrogel Core–Shell Particles

Kronfeld,

Köhler,

Ellinger

2024

J. Compos. Sci.

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An approach is demonstrated for the generation of swellable core–shell particles in the sub-millimeter range using a one-step microfluidic method. Particles are made of an agarose gel core and a shell consisting of hydrogel based on crosslinked poly-(N-isopropylacrylamide) (PNIPAM). Solidification of the core was achieved by cooling below the sol–gel temperature, while the shell was cured by photoinitiated co-polymerization. The shell of the particles is reversibly thermoresponsive; it contracts upon heating, releasing water, and becomes hydrophobic. The transition temperature as well as the stability of the particles are mainly affected by the shell monomer composition, while they are less affected by the type of the core material. Such composite particles remain swellable after drying.

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Section: Introductionmentioning

confidence: 99%

Microfluidic Synthesis and Properties of Thermoresponsive Hydrogel Core–Shell Particles

Kronfeld,

Köhler,

Ellinger

2024

J. Compos. Sci.

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“…These hydrogels are more sensitive to slight changes in environmental factors. Those are called smart hydrogels (Wan et al, 2016;Wu et al, 2016;Katchalsky and Gillis, 1949). 1 show its molecular structure.…”

Section: Introductionmentioning

confidence: 99%

Controlled drug release of levofloxacin from poly (acrylamide) hydrogel

Madhusudana

Mamatha

Demappa

et al. 2021

ijrps

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Hydrogels are 3D polymer networks capable to absorb and release water or biological fluids. They are stimuli-responsive materials, which can show rapid volume changes with response to small changes in environmental parameters such as ionic strength, pH, and temperature. In this work, we performed a synthesis of Poly(acrylamide) hydrogel and tested for controlled release of levofloxacin hemihydrate as a model drug. We used sodium metabisulfite and potassium persulphate as free radical initiators to prepare hydrogel with methylenebisacrylamide as a crosslinker. Characterization of hydrogel was performed by TGA, SEM, and FT-IR. Swelling study and drug release were performed at pH 1.2 and 7.4 solutions, identical to the gastrointestinal fluid at 37°C (human body temperature) to examine possible site-specific drug delivery. UV-Visible spectrophotometer was used to measure the concentration of drug release. Results exhibited the pH and temperature-dependent drug release. The amount of drug release was found to be 17% and 99% in acidic and alkaline pH of 1.2 and 7.4, respectively, after 6 hours.

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“…Polimeric hydrogels which can be modified according to the desired purpose are polymeric materials with many uses such as food industry, personal care products, biomedicine, separation process and water purification. (Peppas et al, 2000;Ganji et al, 2010;Koetting et al, 2015;Sunitha et al, 2015;Singhal and Gupta, 2016;Wan et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Metakrilamid Esaslı Polimerik Hidrojellerin Denge Şişme Çalışmaları

Kundakcı

2019

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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In this study, it was aimed that produce new polymeric hydrogels and that investigate the equilibrium swelling properties. Chemically crosslinked copolymeric hydrogels, composed of methacrylamide (MAAm) and 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) were prepared via free radical copolymerization method. The obtained copolymeric hydrogels were characterized with FT-IR analysis and SEM techniques. In addition, swelling tests 25 o C were applied to all the synthesized samples and swelling characterization studies were performed. The influences of reaction variables such as monomer/co-monomer composition, crosslinker amount on swelling properties of hydrogels were investigated. When the swelling results are evaluated; It was observed that all polymeric samples showed different swelling and diffusion properties depending on their composition.

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Crosslinker effects on swelling and gel properties of pH- and temperature-responsive poly (NIPAM/IA/AM) hydrogels

Cited by 9 publications

References 36 publications

Microfluidic Synthesis and Properties of Thermoresponsive Hydrogel Core–Shell Particles

Microfluidic Synthesis and Properties of Thermoresponsive Hydrogel Core–Shell Particles

Controlled drug release of levofloxacin from poly (acrylamide) hydrogel

Metakrilamid Esaslı Polimerik Hidrojellerin Denge Şişme Çalışmaları

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