Critical attributes of nanofibers: Preparation, drug loading, and tissue regeneration

Stability and solubility of trans-resveratrol are strongly influenced by pH and temperature

“…Therefore, crystalline trans-RSV or solid delivery systems with incorporated trans-RSV are the most appropriate form from the stability point of view, as is also supported by our study using nanofibers as an attractive novel drug delivery system [39].…”

Development and tableting of directly compressible powder from electrospun nanofibrous amorphous solid dispersion

“…Although the direct compression of ASDs might 91 be very complex it was chosen in the present work for forming 92 tablets from fibrous ASD. 93 Electrostatic spinning is a promising technology in the pharma-94 ceutical industry for the production of ASDs for oral drug delivery 95 [20][21][22][23][24][25][26][27][28] or other applications [29][30][31]. Just like the aforementioned 96 two techniques (spray drying and melt extrusion), this is also a 97 continuous technology [32,33].…”

Rotary jet spinning review – a potential high yield future for polymer nanofibers

“…This application exploits the ability of the nanofibers to offer significantly increased surface area to volume ratios than any other material, which is a highly desirable property in this field. Pelipenko et al 98 describe that these novel materials can be employed in the treatment of various diseases as well as in the field of regenerative medicine. The promise is that biological function lost in host tissues will be able to be restored and maintained by tissue engineering through the use of RJS nanofibers.…”