Cribra orbitalia visualized in computed tomography

Exner, S.; Bogusch, Gottfried; Sokiranski, Roman

doi:10.1016/s0940-9602(04)80035-9

Cited by 16 publications

(8 citation statements)

References 2 publications

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“…These bone changes are estimated to be an important indicator of health and nutritional conditions, especially anemia, 5 and many authors have investigated the social health status associated with these changes in various eras and locations. 3,6 The 3D CT scanning studies obtained in the patient in our study indicated cribra orbitalia, results similar to the 3D CT findings in the historic skull reported on by Exner, et al 1…”

Section: Discussionsupporting

confidence: 92%

Entrapment neuropathy of the optic nerve due to hyperostosis associated with congenital anemia

Baba

Minamida²,

Mikami³

et al. 2005

Journal of Neurosurgery

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The authors report on the case of a 14-year-old boy who presented with bilateral visual impairment due to optic canal stenosis caused by hyperplasia of the bone marrow arising from anemia. The patient had hereditary hemolytic anemia with unstable hemoglobin of the Christchurch type. This congenital form of anemia caused hyperplasia of the bone marrow as well as hyperostosis of the entire calvarial bone, which in turn led to optic canal stenosis. The patient underwent surgical decompression of the optic canal, resulting in significant improvement in visual acuity. Pathological findings in the calvarial bone indicated hypertrophic bone marrow with no other specific features such as neoplastic pattern or fibrous dysplasia. With the exception of objective hearing impairment, no other significant cranial neuropathy has been detected thus far. On reviewing the published literature, this case was found to be the first in which hyperostosis due to congenital anemia resulted in symptomatic entrapment neuropathy of the optic nerve. The authors concluded that surgical decompression effectively improves visual acuity.

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Section: Discussionsupporting

confidence: 92%

Entrapment neuropathy of the optic nerve due to hyperostosis associated with congenital anemia

Baba

Minamida²,

Mikami³

et al. 2005

Journal of Neurosurgery

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“…7) are common in bioarchaeological samples. Clinicians, however, rarely report them in living individuals (Exner et al 2004;Rothschild 2012), which limits investigation into the etiologies of the lesions and their association with underlying health and physiological conditions. Paleopathologists commonly attribute both of these lesions to anemia and particularly iron-deficiency anemia.…”

Section: Advances In Our Understanding Of Lesion-formation Processesmentioning

confidence: 99%

“…McIlvaine emphasizes that multiple, interacting etiologies might mask the expression of these lesions, creating hidden heterogeneity in skeletal samples in previously unrecognized ways. Recent applications of computed tomography and microscopy to study the morphological characteristics of cribra orbitalia might stimulate further study of the lesion in living people that would improve our understanding of its etiology and association with other health characteristics (Exner et al 2004;Naveed et al 2012;Schultz 2011). Furthermore, Piperata et al (2014) push for examinations of not just the proximate causes of anemia and resulting skeletal lesions, but also of its ultimate causes and its effects on self-assessments of health.…”

Section: Advances In Our Understanding Of Lesion-formation Processesmentioning

confidence: 99%

The Osteological Paradox 20 Years Later: Past Perspectives, Future Directions

2015

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More than 20 years ago, Wood et al. (Curr Anthropol 33:343-370, 1992) published ''The Osteological Paradox: Problems of Inferring Prehistoric Health from Skeletal Samples,'' in which they challenged bioarchaeologists to consider the effects of heterogeneous frailty and selective mortality on health inferences in past populations. Here, we review the paper's impact on bioarchaeology and paleopathology, focusing on recent advancements in studies of ancient health. We find the paper is often cited but infrequently engaged in a meaningful way. Despite an initial decade of limited progress, numerous researchers are now addressing components of the Paradox in more informed ways. We identify four areas of fruitful research: (1) intrasite, contextual perspectives, (2) subadults, (3) associating stress markers with demographic phenomena, and (4) skeletal lesion-formation processes. Although often seen as a problematic assumption, understanding the sources of heterogeneous frailty within human populations is a worthy research question in and of itself, and one that clearly links past and present health research within a global framework.

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“…46 More recent anthropological studies omitted the parts of the collection from Namibia. 47 The restitutions of 2011 and 2014…”

Section: The Fate Of the Skulls And Skeletons In Berlinmentioning

confidence: 99%

Skulls and skeletons from Namibia in Berlin

Stoecker¹,

Winkelmann²

2018

Human Remains and Violence: An Interdisciplinary Journal

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From 2010 to 2013 the Charité Human Remains Project researched the provenance of the remains of fifty-seven men and women from the then colony of German South West Africa. They were collected during German colonial rule, especially but not only during the colonial war 1904–8. The remains were identified in anthropological collections of academic institutions in Berlin. The article describes the history of these collections, the aims, methods and interdisciplinary format of provenance research as well as its results and finally the restitutions of the remains to Namibia in 2011 and 2014.

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Cribra orbitalia visualized in computed tomography

Cited by 16 publications

References 2 publications

Entrapment neuropathy of the optic nerve due to hyperostosis associated with congenital anemia

Entrapment neuropathy of the optic nerve due to hyperostosis associated with congenital anemia

The Osteological Paradox 20 Years Later: Past Perspectives, Future Directions

Skulls and skeletons from Namibia in Berlin

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