COVID-19 vaccine-induced myocarditis: Case report with literature review

Nassar, Mahmoud; Nso, Nso; Gonzalez, Carlos; Lakhdar, Sofia; Alshamam, Mohsen; Elshafey, Mohammed; Abdalazeem, Yousef; Nyein, Andrew; Punzalan, Benjamin; Durrance, Richard Jesse; Alfishawy, Mostafa; Bakshi, Sanjiv; Rizzo, Vincent

doi:10.1016/j.dsx.2021.102205

Cited by 71 publications

(77 citation statements)

References 35 publications

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“…It should be noted that myocarditis after vaccination is a rare event, and has been described in some vaccines such as the smallpox vaccine [ 8 ] . Concerning the vaccination against COVID-19, several reports were published in this sense, mostly after a mRNA vaccine [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…The symptomatology of myocarditis is varied, ranging from simple shortness of breath, chest pain, or dyspnea to the fulminant myocarditis, in which the patient comes with a shock that usually requires circulatory support with positive inotropes [19]. Regarding myocarditis after mRNA vaccination, according to the Center for Disease Control and Prevention it is recommended to monitor the signs within 7 days after vaccination [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

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Cardiogenic shock revealing myocarditis after mRNA vaccination against covid-19: Case report and brief review for the first case in Morocco

Mimouni

Bahouh

Amaqdouf

et al. 2022

Annals of Medicine &Amp; Surgery

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Introduction and importance: After its unexpected effectiveness in the clinical trials, the anti-COVID-19 vaccine type mRNA was launched on December 11, 2020, but a few months later, several reports of post-mRNA vaccination myocarditis were published, but without any proven causal link. Case presentation We report the case of a 14-year-old teenager admitted to the emergency department for a cardiogenic shock, the patient mentioned that he had an anti-COVID 19 vaccination 10 days before his admission. First, the vasoactive drugs had stabilized the patient; the troponins came back highly favorable but later confirmed myocarditis by magnetic resonance imaging. In this sense an etiological analysis was made and it came back without any particularities, leaving us relating the myocarditis to the vaccination. Clinical discussion Post-vaccination myocarditis is a rare event, with very few reports in the literature. After the introduction of COVID vaccination, several reports were published, mostly after the mRNA vaccine. Until now, no causal link has been proven, so we need to have more reports in this sense to have a better knowledge of this phenomenon. Conclusion Until we obtain a more precise explanation of the mechanism of myocarditis after vaccination with the anti-COVID-19 vaccine, all symptoms suggesting myocarditis should be systematically monitored during the first 7 days after vaccination.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cardiogenic shock revealing myocarditis after mRNA vaccination against covid-19: Case report and brief review for the first case in Morocco

Mimouni

Bahouh

Amaqdouf

et al. 2022

Annals of Medicine &Amp; Surgery

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“…A number of studies have demonstrated post-COVID-19 vaccine-related myositis [12][13][14]. There was also cardiovascular involvement including myocarditis and myopericarditis [15][16].…”

Section: Discussionmentioning

confidence: 99%

COVID-19 Vaccine-Induced Pneumonitis, Myositis and Myopericarditis

Farooq¹,

Mohammed²,

Zafar³

et al. 2022

Cureus

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A 63-year-old male, with no significant past history and not on any regular medications previously, had mild respiratory symptoms post the first dose of the AstraZeneca (Cambridge, England) coronavirus disease 2019 (COVID-19) vaccine, which were self-limiting. Following the second dose of the vaccine, he arrived at the emergency department (ED) with worsening shortness of breath.During this admission, he was assumed to have interstitial lung disease due to a possible past history of occupational exposure. He responded to a short-term course of corticosteroids and antibiotics and was discharged home.However, he reported again to the emergency department three weeks later, with persistent dyspnoea along with myalgia. His blood tests and imaging from scans suggested myositis, pneumonitis, and myopericarditis. Since he recently had the COVID-19 AstraZeneca vaccine, it was postulated as the most likely cause of the symptoms. He was managed with intravenous (IV) corticosteroids followed by oral corticosteroids with symptom resolution.

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“…This is happening because the nanolipid carrier of the mRNA travels directly to the heart, triggering intense inflammation in their heart muscle. [ 59 ] As also noted, this process could result in the production of the spike proteins for months, years, or even for a lifetime. The nanolipid carrier has been shown to enter the brain, liver, spleen, lymph nodes, and kidneys.…”

Section: Vaccines May Increase the Severity Of Covid Symptoms And Overreaction Of The Immune Systemmentioning

confidence: 97%

Covid-19 pandemic: What is the truth?

Blaylock¹

2021

Surgical Neurology International

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The ongoing “pandemic” involving the severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2) has several characteristics that make it unique in the history of pandemics. This entails not only the draconian measures that some countries and individual states within the United States and initiated and made policy, most of which are without precedent or scientific support, but also the completely unscientific way the infection has been handled. For the 1st time in medical history, major experts in virology, epidemiology, infectious diseases, and vaccinology have not only been ignored, but are also demonized, marginalized and in some instances, become the victim of legal measures that can only be characterized as totalitarian. Discussions involving various scientific opinions have been eliminated, top scientists have been frightened into silence by threats to their careers, physicians have lost their licenses, and the concept of early treatment has been virtually eliminated. Hundreds of thousands of people have died needlessly as a result of, in my opinion and the opinion of others, poorly designed treatment protocols, mostly stemming from the Center for Disease Control and Prevention, which have been rigidly enforced among all hospitals. The economic, psychological, and institutional damage caused by these unscientific policies is virtually unmeasurable. Whole generations of young people will suffer irreparable damage, both physical and psychological, possibly forever. The truth must be told.

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COVID-19 vaccine-induced myocarditis: Case report with literature review

Cited by 71 publications

References 35 publications

Cardiogenic shock revealing myocarditis after mRNA vaccination against covid-19: Case report and brief review for the first case in Morocco

Cardiogenic shock revealing myocarditis after mRNA vaccination against covid-19: Case report and brief review for the first case in Morocco

COVID-19 Vaccine-Induced Pneumonitis, Myositis and Myopericarditis

Covid-19 pandemic: What is the truth?

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