Coumarin Derivatives fromEryngium campestre¹

Abstract

Aegelinol benzoate, a new dihydroxanthyletin ester and the known coumarin esters agasyllin and grandivittin, as well as, aegelinol have been isolated from ERYNGIUM CAMPESTRE roots using column chromatography and subsequent semipreparative HPLC. The structures of the compounds have been elucidated by a combination of spectroscopic methods.

Phenolic compounds and rare polyhydroxylated triterpenoid saponins from Eryngium yuccifolium

“…Previous phytochemical investigations on the Eryngium genus indicated the presence of flavonoids (Ikramov et al, 1973;Zarnack et al, 1979;Hiller et al, 1981;Kartnig and Wolf, 1993;Hohmann et al, 1997), essential oil (Brophy et al, 2003;Ayoub et al, 2003Ayoub et al, , 2006Pala-Paul et al, 2005a,b, 2006, coumarins (Erdelmerier and Sticher, 1985), a rosmarinic acid derivative (Le Claire et al, 2005), and saponins (Hiller et al, 1972(Hiller et al, , 1974a(Hiller et al, ,b, 1975(Hiller et al, , 1976a(Hiller et al, ,b, 1977(Hiller et al, , 1978Ikramov et al, 1974;Anam, 2002;Kartal et al, 2005Kartal et al, , 2006. The main saponins from this genus belong to polyhydroxylated triterpenoid glycosides with ester functions.…”

Micropropagation of Eryngium campestre L. via Shoot Culture Provides Valuable Uniform Plant Material with Enhanced Content of Phenolic Acids and Antimicrobial Activity

“…A phytochemical analysis of the above-ground parts resulted in isolation and structural determination of flavonoids: quercetin, isoquercitrin, rutin, luteolin 7-O-β-D-glucopyranoside, astragalin, kaempferol 7-O-α-L-rhamnopyranoside, kaempferol 3,7-di-O-α-L-rhamnopyranoside, kaempferol-3-O-β-D-(2'-p-E-hydroxycinnamoyl)-glucopyranoside, kaempferol-3-O-β-D-(2'-p-Z-hydroxycinnamoyl)-glucopyranoside (Kartnig and Wolf, 1993;Hohmann et al, 1997;Wang et al, 2012). Simple coumarins: aegelinol benzoate, agasyllin, aegelinol and grandivittin occurred in the roots (Erdelmeier and Sticher, 1985;Wang et al, 2012). Essential oil characterized by the presence of monosesqiterpene hydrocarbons, myrcene, germacren and α-pinene was found in the aerial parts of the species (Erdelmeier and Sticher, 1986;Wang et al, 2012).…”

Accumulation of rosmarinic, chlorogenic and caffeic acids in in vitro cultures of Eryngium planum L.

“…The presence of secondary metabolites, such as phenolic acids (rosmarinic, chlorogenic and caffeic acids), triterpenoid saponins, flavonoids (kaempferol and quercetin derivatives) and coumarins is considered to determine its multidirectional pharmacological activities: diuretic, antidiabetic, expectorant, spasmolytic, antiinflammatory, antinociceptive, haemolytic and antimycotic (Duke et al 2002;Kt‹ peli et al 2006). Triterpenoid saponins (Hiller et al 1974;Voigt et al 1985), flavonoids (Hiller et al 1980), chlorogenic acid, rosmarinic acid and its glucoside (Le Claire et al 2005), coumarins (Erdelmeier and Sticher 1985) and essential oil (Thiem et al 2011) have been found in E. planum organs. Rosmarinic acid (RA) and chlorogenic acid (CGA) have been described for many Eryngium species (Le Claire et al 2005).…”