Could peak oxygen uptake be estimated from proposed equations based on the six-minute walk test in chronic heart failure subjects?

Abstract

HighlightsMeasured and estimated VO2peak in CHF patients showed a moderate association.With the exception of equation 1, all equations underestimated VO2peak by up to 51%.The agreement evaluated using Bland–Altman was not consistent.

Using the 6-min Walk Test to Monitor Peak Oxygen Uptake Response to Cardiac Rehabilitation in Patients With Heart Failure

“…Our findings are supported by a recent study evaluating the agreement of prediction equations derived from the 6MWT in patients with HF at a single time point. 11 This study found the Cahalin et al 8 equation to be the most accurate at predicting measured , as compared with the Ross et al 9 and Adedoyin et al 10 equations; however, all equations demonstrated proportional bias according to their Bland-Altman plots. 11 We have extended this finding to a larger sample of patients with HF (n = 54) completing a CR program.…”

“… 11 This study found the Cahalin et al 8 equation to be the most accurate at predicting measured , as compared with the Ross et al 9 and Adedoyin et al 10 equations; however, all equations demonstrated proportional bias according to their Bland-Altman plots. 11 We have extended this finding to a larger sample of patients with HF (n = 54) completing a CR program. The proportional bias and lack of agreement limit the use of prediction equations derived from the 6MWT to estimate actual .…”

“… 7 – 10 Our approach was similar to that of a recently published study. 11 Prediction equations were as follows:…”

“… 5 , 6 There is a known positive correlation between 6MWT distance and ,which has led to the creation of several prediction equations to estimate CRF using the 6MWT distance. 7 – 10 While evidence suggests that the 6MWT and prediction equations using the 6MWT are not valid measures for predicting in the HF population, 11 no study has examined this relationship following CR participation. Therefore, the primary purpose of this report was to assess the agreement between predicted by equations using 6MWT distance and measured by CPX to estimate change in in patients with HF enrolled in CR.…”

Muscle mass and physical recovery in ICU: innovations for targeting of nutrition and exercise

“…Whilst all the indices of physical fitness are correlated to each other, the strength of this relationship is often surprisingly weak[49*] and it is unclear whether alternative approaches will be as effective at predicting adverse outcome as CPET, the technology with the vast majority of data. Data collection for the international multicenter Measuring Exercise Tolerance after Surgery (METS) study [50*] recently completed (target sample size 1723 patients).…”