Cost Analysis of Three Techniques of Administering Sevoflurane

Abstract

Background. This study aimed to evaluate and compare total cost of sevoflurane and propofol for 1.0 MAC-hour of anaesthesia, employing three anaesthetic techniques. Methods. Adult patients scheduled for surgical procedures under general anaesthesia anticipated to last approximately an hour were randomized into three groups (n = 15 each), to receive anaesthesia using one of the following techniques: low flow technique involving induction with propofol, followed by sevoflurane delivered using initial fresh gas flows of 6 L/min till MAC reached 1.0 and then reduced to 0.5 L/min; alternate method of low flow entailing only a difference in fresh gas flow rates being maintained at 1 L/min throughout; the third technique involving use of sevoflurane for both induction and maintenance of anaesthesia. Results. Cost of sevoflurane to maintain 1 MAC-hour of anaesthesia was clinically least with low flow anaesthesia, though statistically similar amongst the three techniques. Once the cost of propofol used for induction in two of the three groups was added to that of sevoflurane, cost incurred was least with the technique using sevoflurane both for induction and maintenance of anaesthesia, as compared to low flow and alternative low flow techniques, a 26% and 32% cost saving, respectively (P < 0.05).

Evaluation of Waste Anesthetic Gas in the Postanesthesia Care Unit within the Patient Breathing Zone

“…The median anesthetic duration and minimum alveolar concentration (MAC) hours were 100 minutes and 2.1, respectively. A MAC hour reflects the calculation of total volatile anesthetic consumption between patients and is calculated by dividing the mL of volatile anesthetic consumed by the duration of 1 MAC anesthesia, as described by Sessler and Badgwell and Tyagi et al [ 8 , 9 ]. Figure 1 shows minimal differences between preoperative vital signs (e.g., systolic blood pressure, diastolic blood pressure, heart rate, and respiratory rate) and their corresponding median PACU Phase I values.…”

The Consumption of Anesthetic Agents During One-lung Ventilation and a Cost Analysis: a Comparison of Two Techniques

“…A literature review revealed many cost-analysis studies of various anesthetic drugs and techniques, but studies focused on OLV were limited. [6,7,[10][11][12][13][14][15] Although the expense of anesthesia accounts for a small part of a single surgical procedure, the total expense constitutes a big budget when the large number of surgeries performed each day is considered. [16] Direct costs related to drugs, medical devices, recovery time, side effects, additional drug administrations,; indirect costs, such as rent, salaries, building equipment costs (fixed costs), and variable costs according to the quantity and quality of the surgical procedures are the main components of total cost analyses.…”

Hemodynamic Stability, Patient Acceptance and Cost of Intravenous Propofol and Inhalational Sevoflurane for Induction of Anaesthesia: A Prospective, Randomized Comparative Study

“…Propofol group patients received IV propofol at a constant rate of 8-10 ml/min till induction. Sevoflurane group patients were explained about mask induction, and sevoflurane was administered through a transparent face mask starting at 0.5% and incrementally increased by 0.5% every 15 sec in 100% O 2 at a total gas flow of 5 L/min via coaxial Bain circuit [6]. Induction was confirmed by loss of eyelash reflex.…”