Hemodynamic Stability, Patient Acceptance and Cost of Intravenous Propofol and Inhalational Sevoflurane for Induction of Anaesthesia: A Prospective, Randomized Comparative Study

Dhande, Kirtibala; Kshirsagar, Jitendra; Dhande, Ashish; Patil, Narendra B.; Parvati,

doi:10.7759/cureus.7687

Cited by 5 publications

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Abolishment of spontaneous breathing, positive pressure ventilation, and the combined effects of anesthetic drugs may explain the reasons why MAP in SIPFR group patients was lower than IVCIS group patients. Blood pressure decreases dose-dependently when administering sevoflurane, due to peripheral vasodilation, decrease in cardiac contractility, disturbance in the function of baroreceptors, and decrease in sympathetic tone [ 17 ]. During inhalational induction, there are two clinical problems.…”

Section: Discussionmentioning

confidence: 99%

Propofol/Fentanyl/Rocuronium or Sevoflurane Inhalational Induction for Intubation?

Mitos¹,

Thoma²,

Tsaousi³

2021

Cureus

View full text Add to dashboard Cite

Introduction Anesthesia induction and airway instrumentation are critical parts of anesthesia administration. Intravenous induction is time convenient but necessitates immediate commencement of ventilation. Inhalational sevoflurane induction takes longer but preserves spontaneous respiration. The primary aim of this study is to evaluate the intubation quality features achieved by sevoflurane as the sole induction agent compared with the standard intravenous induction, involving the use of muscle relaxants. Methods Sixty patients were randomly allocated into two groups: the Inhalational Vital Capacity Induction With Sevoflurane (IVCIS) group (n = 30) in which patients were intubated after sevoflurane inhalational anesthesia with the vital capacity technique and the Standard Intravenous Induction With Propofol, Fentanyl, and Rocuronium (SIPFR) group (n = 30) after propofol 1.5 mg/kg, fentanyl 2 μg/kg, and rocuronium 0.5 mg/kg administration intravenously. Group IVCIS patients were intubated when bispectral index (BIS) < 60 and end-expiratory sevoflurane ≥ 2 minimum alveolar concentration for > eight minutes. Scoring systems were used to evaluate induction and intubation conditions. The Statistical Package for the Social Sciences (SPSS) software version 25.0 (IBM Corp., Armonk, NY) was used for data analysis. Results Intubating and induction conditions were of equal quality in both groups. Sevoflurane induction duration was markedly prolonged. Heart rate was higher in IVCIS group patients throughout the induction, especially during laryngoscopy. Less blood pressure fluctuations were recorded in IVCIS group patients. Conclusions Inhalational vital capacity induction with sevoflurane provided acceptable intubating conditions and exhibited a safe hemodynamic profile, albeit the duration was more than 12 minutes.

show abstract

Section: Discussionmentioning

confidence: 99%

Propofol/Fentanyl/Rocuronium or Sevoflurane Inhalational Induction for Intubation?

Mitos¹,

Thoma²,

Tsaousi³

2021

Cureus

View full text Add to dashboard Cite

show abstract

“…The time for induction of anesthesia was taken as the time from the beginning of the administration of the agent to the loss of finger tapping which is an acceptable outcome in similar studies. 7 8 9 Though bispectral index monitoring was not done, clinical endpoints for recognition of induction like loss of finger tapping to verbal command are valid surrogates for bispectral index monitoring. 10 …”

Section: Discussionmentioning

confidence: 99%

“…There is emerging evidence that inhalational induction using sevoflurane has better hemodynamic stability, equal patient acceptance, and is cheaper than intravenous induction using propofol. 7 Usage of a single inhalational agent for induction and maintenance reduces adverse events accompanying the use of multiple intravenous agents, such as hemodynamic compromise. 17 …”

Section: Discussionmentioning

confidence: 99%

Comparison of vital capacity rapid inhalation and tidal ventilation induction with sevoflurane in adults: a prospective cohort study

et al. 2021

View full text Add to dashboard Cite

Vital capacity rapid inhalation induction (VCRII) results in faster achievement of desired minimum alveolar concentration while reducing the incidence of excitatory phenomenon compared to conventional incremental technique. This study aimed to determine whether the VCRII can achieve faster induction of anesthesia in adults compared to the traditional tidal ventilation (TV) technique. Following the approval from the Institutional Ethics Committee, Amala Institute of Medical Sciences, with an approval No. AIMSIEC/07/2017, on July 1, 2017, 51 adults belonging to American Society of Anesthesiologists physical status I–II, undergoing elective surgery at a tertiary care teaching hospital were prospectively assigned to two groups: 25 in VCRII (38.3 ± 13.3 years old, 20 (80%) females) and 26 in TV inhalation induction (35.2 ± 11.9 years old, 17 (65%) females) using 8% sevoflurane in 66% nitrous oxide. The induction time, such as time (in seconds) to the cessation of voluntary finger tapping, time to loss of eyelash reflex, time to return of regular breathing, the return of conjugate gaze, was measured. The primary outcome was time to induction as defined by time to loss of eyelash reflex. Hemodynamic effects of both methods were compared at baseline and 1, 3, 5, 10, 15-minute intervals from induction. Induction was significantly faster in the VCRII group compared with the TV group in all the measured parameters. Hemodynamic parameters were comparable in both the groups. VCRII resulted in a faster induction time compared to the TV technique in adults.

show abstract

Comparison of Recovery Effect for Sufentanil vs. Remifentanil Anesthesia in Elderly Patients Undergoing Curative Resection for Hepatocellular Carcinoma

Zhang

et al. 2023

Pain Ther

View full text Add to dashboard Cite

Hemodynamic Stability, Patient Acceptance and Cost of Intravenous Propofol and Inhalational Sevoflurane for Induction of Anaesthesia: A Prospective, Randomized Comparative Study

Cited by 5 publications

References 20 publications

Propofol/Fentanyl/Rocuronium or Sevoflurane Inhalational Induction for Intubation?

Propofol/Fentanyl/Rocuronium or Sevoflurane Inhalational Induction for Intubation?

Comparison of vital capacity rapid inhalation and tidal ventilation induction with sevoflurane in adults: a prospective cohort study

Comparison of Recovery Effect for Sufentanil vs. Remifentanil Anesthesia in Elderly Patients Undergoing Curative Resection for Hepatocellular Carcinoma

Contact Info

Product

Resources

About