Correlation of the breeds and dental lesions in cattle of northern Iran

Salehi, Alireza; Rahimi, Omid; Masoumi, Mohammadreza; Dehghani, Maryam; Niaki, Seyedeh Talayeh Mostafavi; Yazdanpanah, Tina; Nabavi, Atefeh Sadat; Mehravar, Shabnam

doi:10.1007/s00580-023-03440-x

Cited by 3 publications

(3 citation statements)

References 5 publications

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“…Additionally, Kruskal–Wallis and Mann–Whitney U tests were used for histopathological scoring differences between the groups. The statistical comparisons were analyzed through SPSS 26 version [ 25 , 45 ].…”

Section: Methodsmentioning

confidence: 99%

Effect of Rosa damascena Extract on Rat Model Alzheimer’s Disease: A Histopathological, Behavioral, Enzyme Activities, and Oxidative Stress Study

Hejazian

Hosseini

Taravati

et al. 2023

Evidence-Based Complementary and Alternative Medicine

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The purpose of the current study is to investigate the effect of aquatic Rosa damascena extract against the oxidative damage induced by aluminum chloride intoxication in Alzheimer’s model of Wister rats. Rats were divided randomly into seven groups (n = 10). Control group received no treatment, sham group received distilled water orally, aluminum group (AL) was administered AlCl3 (100 mg/kg) orally, extract 1 and 2 groups were treated with only aqueous R. damascena extract (DRE) (500 and 1000 mg/kg), and treatment 1 and 2 groups received aqueous R. damascena extract (500 and 1000 mg/kg) and AlCl3 (100 mg/kg) orally. The brain tissues were sampled for histopathological examination, and biochemical analysis was conducted for estimating the enzyme activities of acetylcholinesterase and catalase (CAT), the levels of GSH and MDA, and ferric reducing antioxidant power. According to the results of behavioral tests, AL administration showed a reduction in spatial memory and remarkably increased the time needed for reaching the invisible platform. The administration of Al-induced oxidative stress and an increase of the enzyme activity of AChE. Al administration increased AChE level from 1.176 ± 0.173 to 3.62 ± 0.348, which was a significant rise. However, treating with the extract at the dose of 1000 mg/kg downregulated it to 1.56 ± 0.303. Administration of the R. damascene extract caused an increased level of catalase and glutathione levels in treatment groups, attenuated MDA level, and regulated AChE activity. Our results illustrate that administration of R. damascene extract has a protective effect against the oxidative damage induced by AlCl3 intoxication in Alzheimer’s model.

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Section: Methodsmentioning

confidence: 99%

Effect of Rosa damascena Extract on Rat Model Alzheimer’s Disease: A Histopathological, Behavioral, Enzyme Activities, and Oxidative Stress Study

Hejazian

Hosseini

Taravati

et al. 2023

Evidence-Based Complementary and Alternative Medicine

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“…Te MTT results were analyzed by employing Graphpad Prism software version 9. P < 0.05 was considered signifcant [33][34][35]. Te one-way ANOVA and the post hoc Tuckey test were employed to compare the diferences between diferent cell groups [36,37].…”

Section: Discussionmentioning

confidence: 99%

Potential of Natural Antioxidants for Upregulating Apoptosis in Cervical Cancer Cells: A Cellular and Molecular Study

Salehi,

Faraji,

Shafaei

et al. 2023

Journal of Chemistry

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Natural antioxidants (NAs) are promising substances, which are established as potent therapeutic agents. However, the anticancer potential of many of them is not completely known. In this research, the anticancer effect of three natural antioxidants including geraniol (Ge), citronellol (Cit), and quercetin (Qu), and their combination by estimating their cytotoxicity on the Hela cells at doses from 15.625 to 1000 µg/mL was investigated. Moreover, cisplatin (Cis) was employed as a strong competitive comparison. After estimating the IC50 value of each treatment in the MTT assay, western blot was performed with the obtained doses for further evaluation. In this regard, the expressions of caspase3, Bax, Bcl2, and p53 proteins were examined. Our results showed that the combination of these natural substances had significant cytotoxic potential by upregulating all mentioned proteins, which demonstrated the apoptosis pathway. Our findings had also the same results in both Cis-receiving and non-Cis-receiving cells regarding some indices. Consequently, it was suggested to further investigate these natural antioxidants as both main or adjuvant therapies for their anticancer potential and side-effect reduction in vivo. Overall, it can be concluded that these natural antioxidants are effective against cancer cells by upregulating the apoptosis pathway.

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“…Also, it should be noted that rodents are unlikely to be infected with rabies [ 5 ]. In northern Iran, most cows are mixed-breed including mixed Simmental and mixed Holstein [ 6 ]. They are the main source of meat, dairy products, and consequently income [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Rabies Cases Received by the Shomal Pasteur Institute in Northern Iran: A 2-Year Study

et al. 2023

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The rabies virus, which belongs to the genus Lyssavirus, the family Rhabdoviridae, is the causative agent of rabies, a contagious, deadly, and progressive neurological infection. This illness is commonly distributed worldwide and affects all warm-blooded animals. Regarding the zoonotic aspects of rabies, the prevalence of rabies was investigated in this study. Over 2 years, 188 samples were examined via the direct fluorescent antibody test (DFAT) and mouse inoculation test (MIT) techniques by using brain tissue samples. Our findings showed that 73.94% of samples were rabies positive. The highest number of samples belonged to cows and dogs, respectively. The positivity rate in cows was 71.88%, followed by dogs with a 57.78% infection rate. These findings suggested that despite the heavy monitoring protocols in Iran, rabies is still a prevalent disease, and it is advised that vaccinations and screening programs should be carried out more frequently with heavier observation.

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Correlation of the breeds and dental lesions in cattle of northern Iran

Cited by 3 publications

References 5 publications

Effect of Rosa damascena Extract on Rat Model Alzheimer’s Disease: A Histopathological, Behavioral, Enzyme Activities, and Oxidative Stress Study

Effect of Rosa damascena Extract on Rat Model Alzheimer’s Disease: A Histopathological, Behavioral, Enzyme Activities, and Oxidative Stress Study

Potential of Natural Antioxidants for Upregulating Apoptosis in Cervical Cancer Cells: A Cellular and Molecular Study

Comparison of Rabies Cases Received by the Shomal Pasteur Institute in Northern Iran: A 2-Year Study

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