Correlation of Serum Magnesium with Dyslipidemia in Maintenance Hemodialysis Patients

Abstract

One of the factors involved in accelerated atherosclerosis in hemodialysis patients is dyslipidemia. In this study we considered factors involved in intensification of dyslipidemia in hemodialysis patients.This study was done on 36 maintenance hemodialysis patients. Serum lipoprotein (a), Triglyceride, Cholesterol, HDL-C,LDL-C and also serum Intact parathormone( iPTH), Calcium, Phosphorus, Magnesium were measured. In statistical analysis there was not any correlation between serum lipids and iPTH. There was not correlation between serum calcium with serum lipids (p>0.05). There was not correlation between CaxP product with serum lipids (p>0.05). There was a positive correlation between serum Magnesium and Lipoprotein(a) (P<0.05) and also positive correlation between serum magnesium with triglyceride level (P<0.05) was seen too. Magnesium doesn’t increase the lipoprotein synthesis. It may involve in the regulation of some enzymes responsible for lipoprotein synthesis. Correlation of serum magnesium with serum triglycerides can be due to changes in hepatic triglyceride metabolism. Lipoprotein(a) is a non traditional factor of premature atherosclerosis, its association with serum magnesium needs more attention in hemodialysis patients.

Ketosis in buffalo (Bubalus bubalis): clinical findings and the associated oxidative stress level

“…HDL-cholesterol level showed a significant decrease in ketotic buffalo in comparison to the subclinical and control groups. These results coincide with those of Nasri and Baradaran (2004) and Turk et al (2008). These results may be attributed to moderate liver steatosis, which causes reduction in cholesterol level.…”

Hypomagnesemia and atherogenic dyslipidemia in chronic kidney disease: surrogate markers for increased cardiovascular risk

“…We also observed an association of lowered magnesium concentration with atherogenic dyslipidemia, an important adverse risk factor for the development of cardiovascular disease. This is in contrast to the findings of Baradaran et al [30] who found no existent correlation between lipid profile and serum magnesium, but in concordance with Ansari et al [31], who identified an association of triglycerides alone with serum magnesium and animal studies and other human studies which show a positive correlation and amelioration of dyslipidemia on supplementation of magnesium [32][33][34].…”

Gender differences in the effect of fish oil on appetite, inflammation and nutritional status in haemodialysis patients

“…The effect may be mediated through anti‐inflammatory mechanisms because leptin has structural and functional similarities with members of the cytokine family (Pecoits‐Filho et al. , 2003) and enhances cytokine production by macrophages and monocytes (Nasri & Baradaran, 2005). This indicates that fish oil may be an effective therapy for improvement of appetite in dialysis patients and warrants future research.…”