Abstract:In eyes with acute zonal occult outer retinopathy, the mean blur rate at the affected area significantly increases along with improvement of visual functions. These results suggest that impaired choroidal circulation is involved in the pathogenesis of acute zonal occult outer retinopathy.
“…S1A; right, dotted line). To evaluate changes in average MBR, the changing rate of average MBR against the initial baseline value was used, as previously described, 17,[19][20][21][22][23][24][25][26] since the MBR is an index of ''relative'' blood flow velocity. …”
Section: Mean Blur Rate Measurements On Lsfgmentioning
“…S1A; right, dotted line). To evaluate changes in average MBR, the changing rate of average MBR against the initial baseline value was used, as previously described, 17,[19][20][21][22][23][24][25][26] since the MBR is an index of ''relative'' blood flow velocity. …”
Section: Mean Blur Rate Measurements On Lsfgmentioning
“…5 Although LSFG does not provide an absolute value for the blood flow, this technique has the advantage of allowing precise and repeated measurements of choroidal circulation at various intervals during the time course of diseases. 4 We have recently revealed that the MBR decreased in the acute stage of the choroidal inflammatory diseases, including Vogt-Koyanagi-Harada disease 6 and acute zonal occult outer retinopathy, 7 whereas it increased in acute central serous chorioretinopathy 8 due to a noninflammatory (i.e. sympathetic or adrenergic) etiology.…”
“…Each average MBR was automatically calculated for each square using the software. To evaluate changes in average MBR, the changing rates of average MBR against the initial baseline values (defined as 100 %) were used, as previously described [11][12][13], since MBR is a quantitative index of the "relative" blood flow velocity.…”
Section: Ophthalmologic Examinationsmentioning
confidence: 99%
“…Recently, laser speckle flowgraphy (LSFG) has been used to investigate ocular blood flow velocity [7][8][9][10][11][12][13]. The wavelength of 830 nm for a diode laser used in LSFG can penetrate deep into the choroid, as demonstrated in composite color map images depicting the large choroidal vessels.…”
Section: Introductionmentioning
confidence: 99%
“…We have recently demonstrated using LSFG that choroidal blood flow velocity increased with regression of AZOOR [13], acute macular neuroretinopathy [10], and punctate inner choroidopathy [18], another clinical entity in the AZOOR complex. These observations led us to hypothesize that choroidal blood flow impairment relates to the pathogenesis of MEWDS as well.…”
These results, in concert with angiographic findings, are likely to reinforce the concept of choroidal circulation impairment as a predisposing factor for MEWDS.
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