Decreased choroidal blood flow velocity in the pathogenesis of multiple evanescent white dot syndrome

Abstract

These results, in concert with angiographic findings, are likely to reinforce the concept of choroidal circulation impairment as a predisposing factor for MEWDS.

Pulse Waveform Changes in Macular Choroidal Hemodynamics With Regression of Acute Central Serous Chorioretinopathy

“…S1A; right, dotted line). To evaluate changes in average MBR, the changing rate of average MBR against the initial baseline value was used, as previously described, 17,[19][20][21][22][23][24][25][26] since the MBR is an index of ''relative'' blood flow velocity. …”

“…The macular MBR, largely derived from the choroid, 16 has been used to evaluate choroidal hemodynamics in various diseases. [17][18][19][20][21][22][23][24][25][26] Our recent study on CSC demonstrates that the macular MBR increases at the acute stage, 19 reinforcing the suspected role of choroidal hyperperfusion in the development of acute CSC. 10 With recent advances of LSFG, various parameters can be automatically calculated to analyze the pulse waveform of MBR averaged in a single heartbeat, 14,[27][28][29][30][31] including the skew, blowout time (BOT), and acceleration time index (ATI), all of which are expressed as absolute values.…”

Choroidal vascularity index changes after vitreomacular surgery

“…Its level of vascularization has been implicated in the pathogenesis of a large number of posterior segment diseases of the eye, such as age-related macular degeneration, central serous chorioretinopathy, myopic macular degeneration and macular oedema (Grossniklaus & Green 2004;Gomi & Tano 2008;Fujiwara et al 2009;Chung et al 2011). Nevertheless, a certain disparity in CT measurements exists among the various clinical studies (Hirose et al 2008;Saito et al 2014;Hashimoto et al 2015). CT has been reported to be an indicator of ocular and systemic health and is considered to be an important parameter for investigating various choroid pathogeneses (Lindner et al 2015;Tseng & Chen 2015;Kim et al 2013;Wong et al 2013;Ahn et al 2014;Tan et al 2016a,b;Wei et al 2017).…”

Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma

“…Changes in the blood flow and thickness may be manifestations of a process with an “inflammatory” pattern occurring in the choroid [18, 25]. Similarly, these changes have been also observed in unilateral acute idiopathic maculopathy [20], acute posterior multifocal placoid pigment epitheliopathy [26], and acute zonal occult outer retinopathy complex [17, 19, 27–30]. In contrast, both the blood flow velocity and thickness increased in the acute stage of central serous chorioretinopathy [16, 31], which involves a sympathetic or adrenergic etiology.…”