Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma

Abstract

Background: Choroidal circulation hemodynamics in eyes with ocular blunt trauma has not been quantitatively examined yet. We quantitatively examined changes in choroidal blood flow velocity and thickness at the lesion site using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT) in a patient with chorioretinopathy associated with ocular blunt trauma. Case presentation: A 13-year-old boy developed a chorioretinal lesion with pigmentation extending from the optic disc to the superotemporal side in the right eye after ocular blunt trauma. The patient's best-corrected visual acuity (BCVA) was 0.2 in the right eye. Indocyanine green angiography showed hypofluorescence from the initial phase, with a decrease of mean blur rate (MBR) on LSFG color map, which corresponded to the chorioretinal lesion. The BCVA and foveal outer retinal morphologic abnormality spontaneously improved during follow-up. MBR and choroidal thickness increased by 23-31% and 13-17 μm at the lesion site and by 11-22% and 33-42 μm at the fovea, respectively, during the 6-month follow-up period after baseline measurements in the affected eye. In contrast, these parameters showed little or no changes at the normal retinal site in the affected eye and the fovea in the fellow eye. Conclusions: Current data revealed that both blood flow velocity and thickness in the choroid at the lesion site decreased in the acute stage and subsequently increased together with improvements in visual function and outer retinal morphology. These results suggest that LSFG and EDI-OCT may be useful indices that can noninvasively evaluate activity of choroidal involvement in ocular blunt trauma-associated chorioretinopathy.

Macular perfusion changes assessed with optical coherence tomography angiography after vitrectomy for rhegmatogenous retinal detachment

“…Furthermore, we found that the patients with worse visual outcome appeared to have abnormal ellipsoid zone structure associated with the relatively descending choroidal blood flow. It had been reported that the increase in BCVA accompanied with the improvement in outer retinal morphology was significantly correlated with the macular choroidal circulation elevation in eyes with acute zonal occult outer retinopathy, m u l t i p l e e v a n e s c e n t w h i t e d o t s y n d r o m e , a n d chorioretinopathy associated with ocular blunt trauma [24][25][26]. Furthermore, the choriocapillaris layer beneath the disrupted ellipsoid zone of the photoreceptor had greater areas of flow void than the area beneath an intact ellipsoid zone in ischemic maculopathy [27].…”

Increased thickness and decreased blood flow velocity of the choroid in a patient with acute macular neuroretinopathy

“…In contrast, the thickness and blood flow velocity concurrently decreased with regression of acute central serous chorioretinopathy (sympathetic pattern) [18, 19]. Moreover, both of the parameters increased with regression of commotio retinae (vaso-occlusive pattern) [20, 21]. Importantly, changes in the thickness and blood flow during disease regression correlated inversely in Vogt-Koyanagi-Harada disease and positively in central serous chorioretinopathy [7, 19].…”

Incidence of Epiretinal Membrane Formation After Pars Plana Vitrectomy for Giant Retinal Tear-Associated Retinal Detachment

“…13,15 The incidence of ERM formation after PPV for a routine RRD repair is reported between 6% and 28.5% and primary ILM peeling at the time of RRD repair has been shown to prevent ERM formation. 12,[14][15][16][17] While previous studies have shown that a large retinal tear may correlate with an ERM formation, 17,18 a report on the incidence of postoperative ERM formation after primary vitrectomy for GRT-RD repair is scarce and yet to be highlighted. We report a retrospective, single-institution, consecutive case series evaluating the incidence of postoperative ERM after primary PPV for GRT-RD repair as well as clinical characteristics and visual outcomes at a level-one trauma and tertiary referral academic center.…”