Correction: Tickner, Z.J.; Farzan, M. Riboswitches for Controlled Expression of Therapeutic Transgenes Delivered by Adeno-Associated Viral Vectors. Pharmaceuticals 2021, 14, 554

Tickner, Zachary J; Farzan, Michael

doi:10.3390/ph14121271

Cited by 4 publications

(3 citation statements)

References 2 publications

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“…Riboswitches aid in generating viral vectors for gene therapy as well as the anti‐transgenic immune response, creating a multifunctional toolset for regulating expression in gene therapy. [ 5 ] Several research have demonstrated that the ribozyme‐based artificial riboswitch improves viral vector‐mediated gene therapy and regulation efficiency in humans and animals. [ 242 ] This riboswitch was constructed by fusing an RNA aptamer with a self‐cleaving ribozyme.…”

Section: Multidimensional Applications Of Riboswitchesmentioning

confidence: 99%

“…They can respond to a wide range of endogenous and non-endogenous small molecules, making them versatile tools for various applications. While there have been several key review articles on the applications of riboswitches, with emphasis on bioimaging, gene therapy, drug targets, and food safety detection, [4][5][6][7] a full treatment of the latest advances merits a separate review. This article focuses on riboswitch applications in…”

Section: Introductionmentioning

confidence: 99%

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Multidimensional Applications and Challenges of Riboswitches in Biosensing and Biotherapy

Wu,

Zhu,

Zhang

et al. 2023

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Riboswitches have received significant attention over the last two decades for their multiple functionalities and great potential for applications in various fields. This article highlights and reviews the recent advances in biosensing and biotherapy. These fields involve a wide range of applications, such as food safety detection, environmental monitoring, metabolic engineering, live cell imaging, wearable biosensors, antibacterial drug targets, and gene therapy. The discovery, origin, and optimization of riboswitches are summarized to help readers better understand their multidimensional applications. Finally, this review discusses the multidimensional challenges and development of riboswitches in order to further expand their potential for novel applications.

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Section: Multidimensional Applications Of Riboswitchesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Multidimensional Applications and Challenges of Riboswitches in Biosensing and Biotherapy

Wu,

Zhu,

Zhang

et al. 2023

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“…Ed. 2020, 59, 22414, doi:10.1002/anie.202009240 was not cited [1]. The citation has now been inserted in Section 2.8: Regulation of CRISPR-Cas Activity by Riboswitches, paragraph 2, and should read: A particularly interesting case was recently reported by Renzl et al, who incorporated aptamers to the photoreceptor PAL into gRNAs and demonstrated 546-fold regulation of mRNA levels in response to light in HeLa cells [190].…”

Section: Missing Citationmentioning

confidence: 99%