Riboswitch-mediated regulation of riboflavin biosynthesis genes in prokaryotes

Regulatory RNAs in Bacillus subtilis: A review on regulatory mechanism and applications in synthetic biology

“…In addition to regulating their natural targets, regulatory RNAs such as riboswitches and sRNAs have been structurally redesigned and developed as efficient and independent regulatory tools in prokaryotes to regulate non-natural target gene expression via the canonical or noncanonical regulation mechanism [ [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] ]. CRISPR RNAs (clustered regularly interspaced short palindromic repeat RNAs), essential components of the bacterial innate immune system against bacteriophage, guide Cas proteins (CRISPR-associated proteins) to targeted DNA or RNA sequences.…”