Coronary Artery Disease in Patients With Psoriasis Referred for Coronary Angiography

Increased Prevalence of Coronary Artery Disease in Severe Psoriasis and Severe Atopic Dermatitis

“…Coherently, the prevalence of coronary artery disease risk genes are increased in patients with psoriasis 37 . A retrospective study linking records of patients undergoing coronary angiography with dermatology records demonstrated that patients with psoriasis were more likely to have coronary artery disease (84.3% vs. nonpsoriatics: 75.7%, P=0.005) at coronary angiography 38 . Until now, cardiac CT has only been applied in patients with psoriasis using non-contrast enhanced CT.…”

Mean platelet volume, neutrophil to lyphocyte ratio and platelet to lymphocyte ratio in psoriasis

“…Psoriasis hastalarında diabetes mellitus, atrial fibrilasyon, hipertansiyon, aterosklerozis, stroke, miyokard enfarktüsü, kardiyovasküler mortalite ve metabolik sendrom oranlarının yüksek olduğu uzun zamandır bilinen bir gerçektir [2][3][4][5][6][7] . Son yıllarda nötrofil ve trombosit sayısının lenfosit sayısına (N/L ve T/L oranı) oranının sistemik inflamasyonun bir göstergesi olabileceği ve birçok kardiyovasküler hastalık, maliniteler ve kronik inflamatuvar hastalıklarda prognoz ile ilişkili olduğu gösterilmiştir.…”

Antidrug antibodies in psoriasis: a systematic review

“…1,2 Although the pathogenesis of psoriasis is poorly understood, upregulation of T-helper (Th)1 and Th17 pathways resulting in increased levels of tumour necrosis factor (TNF)-a and interleukin (IL)-23 has been implicated. [3][4][5] Through the growing understanding of the pathogenesis of psoriasis, treatments have evolved from topical agents to biological therapies including fusion proteins and monoclonal antibodies.…”