Cord blood full blood count parameters in Lagos, Nigeria

Abstract

IntroductionFull blood count (FBC), one of the most frequently requested for laboratory investigations, is a simple, fast and cheap test and is a reliable indicator of health. Due to its usefulness in the assessment of health status of individuals, its parameters in cord blood, a major source of haemopoietic stem cell transplantation and an ideal source for laboratory investigations for newborns were determined to provide a useful guide to local neonatologists and stem cell transplant physicians.MethodsThree millilitres of umbilical cord blood was collected from 130 normal birth weight newborns (69 males and 61 females) whose cord were clamped immediately after delivery, at a teaching hospital in Lagos, Nigeria and full blood count parameters were determined using Sysmex autoanalyzer, model KX-21N. Consented mothers of the newborns were selected based on, age between 18 and 45 years; uneventful pregnancy and delivery and haemoglobin (Hb) concentration ≥ 10 g/dL.ResultsThere were no statistical gender differences in the mean values of Hb concentrations (M = 13.27 ±1.60 g/dL; F = 13.32±1.61g/dL; p = 0.93), total white cell count (M = 3.16±5.43 × 109/L; F = 13.07±4.98 × 109/L; p= 0.92), platelet count (M= 223.64± 64.21 × 109/L; F = 226.69±80.83 × 109/L; p = 0.81) and other parameters.ConclusionMean values of full blood count parameters obtained in this study are comparable to reports from other studies in developing countries and could be a useful guide for neonatologists and stem cell transplant physicians in our geographical location.

Reference Ranges for Hematological Values in Umbilical Cord Blood in Pokhara, Nepal

“…showed reference values which were lower than the ones seen in our study (8.8±2.9; 13.29±1.5; and 11.2±1.5 gm/dl respectively 1,11,12 . In contrast, a study from Scandinavia had reported much higher hemoglobin values (19.3±2.2gm/dl) than seen in our study 13 .…”

“…he Complete Blood Count CBC parameters varies with age, race, sex, diet, drugs, analytical methods and other various factors and therefore, the concept of an universal "normal" value of complete blood count has changed to reference values for a given population 1,2,3 . This means that it is important to carry out studies to establish standard reference values for the local population 3 .Complete blood count (CBC) is one of the most commonly carried out investigation when assessing the health status of an individual; not only is it a simple investigation to carry out, it is also relatively fast, cost effective and a reliable indicator of the health of a person 1 .…”

“…This means that it is important to carry out studies to establish standard reference values for the local population 3 .Complete blood count (CBC) is one of the most commonly carried out investigation when assessing the health status of an individual; not only is it a simple investigation to carry out, it is also relatively fast, cost effective and a reliable indicator of the health of a person 1 .…”

“…White blood cell (WBC) and platelets are responsible for providing information regarding sepsis and hemostatic status 1 .…”

Hematological profile including alkali resistant hemoglobin of neonates at birth using cord blood in relation to gestational age and maternal diseases

“…The mean corpuscular volume (MCV) is higher in our population than in Iranian and Italian studies. [15][16][17] The haematologic parameters also exhibit statistically significant deviation in mothers affected by anaemia, hypertension and gestational diabetes. There is a wide variation in leucocyte count.…”