Reference Ranges for Hematological Values in Umbilical Cord Blood in Pokhara, Nepal

Basnet, Sahisnuta; Singh, Sandip K.; Sathian, Brijesh; Mishra, Ravi Shankar

doi:10.3126/jnps.v36i2.15605

Cited by 9 publications

(20 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Hgb values (13.3-19.6 g/dl) of this study almost agrees with a study reported in Saudi Arabia (15.7-19.7 g/ dl), however, the upper limit of platelet value (413 × 10 9 /l) the present study was greater than as compared to the upper limit of Saudi reported (297 × 10 9 /l) [20]. On the other hand, Our finding of the 95% RI of RBC (3.69-5.47) values was comparable to a study reported in Nepal (3.67-4.93) [21], Iran (3.61-5.29) [22], and Nigeria (3.52-4.62) [23] reported. Similarly, the 95% RI of WBC (7.64-22.16 × 10 9 /l) in our study similar to the study conducted in Turkey (71.90-25.44 × 10 9 /l) [24].…”

Section: Discussioncontrasting

confidence: 58%

Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

2020

View full text Add to dashboard Cite

Background: Hematological reference intervals are used for medical decision tools for interpretation of numerical test results. Establishing of hematological interval among newborn babies is very important for the diagnosis of malignancy, anemia, bleeding disorders, and various infections. There are no locally established hematological reference intervals in Ethiopia. Thus, the aim of this study is to establish locally determined hematological reference interval among full-term newborns. Methods: A cross-sectional study was conducted from May 15 to July 30 2019 among 151 apparently healthy fullterm newborns at Gondar University Hospital. About 3 ml of cord blood was obtained for analysis of Hematological parameters and determined by using Sysmex KX-21N (Sysmex Corporation Kobe, Japan) automated analyzer. Median, 2.5th and 97.5th percentile were computed. Result: Male to female ratio was almost equal. All hematological parameter had no statistically significant difference between males and females. The delivery types were not influenced its hematological values. The reference interval of white blood cells, red blood cells, platelets, hemoglobin, hematocrit, mean cell volume, and mean cell hemoglobin were (7.64-22.16) x10 9 /l, (3.69-5.47)x10 12 /l, (132.74-413.4) x10 9 /l, (13.32-19.64) g/dl and (39.42-58.06)%, (91.6-113.22)fl, and (30.48-38.02 pg), respectively. Conclusions: All hematological reference intervals were established from full-term newborns at University of Gondar hospital was different from other studies in Nigeria, Iraq, Pakistan, Nepal, Saudi Arabia and Iran. Therefore, own determined reference value is very important for the clinicians to correctly diagnosis the patients at health facility levels.

show abstract

Section: Discussioncontrasting

confidence: 58%

Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

2020

View full text Add to dashboard Cite

show abstract

“…x10 9 /l) (23) and Sagamu Nigeria (4.3 x10 9 /l). On the contrarily, the higher limit of RI of Hgb value (19.6g/dl) of this study was consistent to a study reported in Saudi Arabia (19.7g/dl) (23) but higher than in a study reported in Logas Nigeria (14.8g/dl) (17), Pakistan (17.3g/dl) (25), Iraq (15.22g/dl) (26), and Nepal (17.2g/dl) (18). The difference of Hgb value might be due to method variation, inclusion criteria of the study participants and time of cord clamping.…”

Section: Discussionsupporting

confidence: 92%

“…The of Hgb values (13.3-19.6g/dl) of this study almost agrees with a study reported in Saudi Arabia (15.7-19.7g/dl), however, the upper limit 97.5 th percentiles of platelet value (413 x10 9 /l) the present study was greater than as compared to the upper limit of Saudi reported (297 x10 9 /l) (23). On the other hand, Our nding of the 95% RI of RBC (3.69-5.47) values were comparable to a study reported in Nepal (3.67-4.93) (18), Iran (3.61-5.29) (19), and Nigeria (3.52-4.62) (20) reported. Similarly, the 95% RI of WBC (7.64-22.16 x10 9 /l) in our study similar to the study conducted in Turkey ( 71.90-25.44 x10 9 /l) (24).…”

Section: Discussionsupporting

confidence: 88%

“…on the contrary, the lower limit of WBC was higher than a study reported in Sagamu, Nigeria (4.2) (20) and Iran (5.16) (19). However, the MCH RI (30.5-38.02) were similar to a study done in Saudi Arabia (30.2-40.6)(23), Nepal (31.6-36.2), (18), and Pakistan (32.2-35.4) (25). On the other hand, the Hct value (39.4-58.1) of the current study was comparable to a study conducted in Iran (39.6-56.9) (19).…”

Section: Discussionsupporting

confidence: 84%

“…The lower limit WBC (7.64) value of this study was lower than a study reported in Saudi Arabia (10.9) (23), Nepal (10.49) (18) and Pakistan (9.7) (25). on the contrary, the lower limit of WBC was higher than a study reported in Sagamu, Nigeria (4.2) (20) and Iran (5.16) (19).…”

Section: Discussioncontrasting

confidence: 75%

See 2 more Smart Citations

Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

Tiruneh

Kiros

Getu

2020

Preprint

View full text Add to dashboard Cite

Background: Hematological reference intervals are used for medical decision tools for interpretation of numerical test results. Establishing of hematological interval among newborn babies is very important for the diagnosis of malignancy, anemia, bleeding disorders, and various infections. There is no locally established hematological reference intervals in Ethiopia. Thus, the aim of this study is to established locally determined hematological reference interval among full-term newborns.Methods: A cross sectional study was conducted from February to May 2019 among 151 apparently healthy full-term newborns at Gondar University Hospital. About 3ml of cord blood was obtained for analysis of Hematological parameters and determined by using Sysmex KX-21N (Sysmex Corporation Kobe, Japan) automated analyzer. Median, 2.5th and 97.5th percentiles were computed.Result: Males to female’s ratio was almost equal. All hematological parameter had no statistically significant difference between males and females. The delivery types were not influenced its hematological values. The reference interval of white blood cells, red blood cells, platelets, hemoglobin, hematocrit, mean cell volume, and mean cell hemoglobin were (7.64-22.16) x109/l, (3.69-5.47)x1012/l, (132.74-413.4) x109/l, (13.32-19.64) g/dl and (39.42-58.06)%, (91.6-113.22)fl, and (30.48-38.02)pg, respectively.Conclusion: All hematological reference interval was established from full-term newborns at University of Gondar hospital was different from other studies in Nigeria, Iraq, Pakistan, Nepal, Saudi Arabia and Iran. Therefore, own determined reference value is very important for the clinicians to correctly diagnosis the patients at health facility levels.

show abstract

Tunisian Newborn's Cord Blood: Reference Values of Complete Blood Count and Hemoglobin Fractions

et al. 2020

View full text Add to dashboard Cite

Objective This study was aimed to establish local reference values for hematological indices and hemoglobin (Hb) fractions in umbilical cord blood (UCB) for the northern population of Tunisia. Study Design Our study included full-term newborns by vaginal deliveries. Hematological parameters were collected using an automated blood cell counter. The amounts of Hb fractions were measured by capillary electrophoresis of Hb. Statistical analysis was performed using R software. Results A total of 328 cord blood samples were analyzed. Among them, 154 (male: 44.8%, female: 55.2%) were used to establish reference values. The normal reference values of complete blood count (CBC) and Hb fractions were calculated. Mean neonatal Hb was 14.75 ± 2.26 g/dL. Gestational age affects the expression of CBC values as red blood cell (RBC), Hb, hematocrit (Hct), mean corpuscular volume (MCV), white blood cell (WBC), and the Hb profile. Umbilical blood hemogram parameters and Hb profile are affected by the environment; higher in newborns from urban regions but not affected by gender ratio. Conclusion Reference ranges of normal CBC indices and Hb fractions have been successfully established in Tunisian neonates' UCB. Our data suggest reference values that could be useful for neonatal patients' laboratory results and clinical interpretation. Key Points

show abstract

Reference Ranges for Hematological Values in Umbilical Cord Blood in Pokhara, Nepal

Abstract: Introduction: Reference hematological values in newborns

Cited by 9 publications

References 5 publications

Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

Tunisian Newborn's Cord Blood: Reference Values of Complete Blood Count and Hemoglobin Fractions

Contact Info

Product

Resources

About