Hematological profile including alkali resistant hemoglobin of neonates at birth using cord blood in relation to gestational age and maternal diseases

Abstract

Background: The importance of complete hemogram along with the hematological indices in the diagnosis of neonatal health cannot be overemphasized. There is a severe paucity of relevant data regarding neonatal hematological profile in relation to gestational age and maternal diseases in this part of the country. With this perspective, the authors intended to do a pilot study to analyse the haematological profile of neonates of different gestational ages and different maternal diseases born in a teriary care hospital in Eastern India.Methods: This is a cross sectional study design based on cord blood sample of newborns and their mothers recruited from those admitted in the gynae and obstetric department in IPGME&R. The umbilical cord blood was collected from the newborn babies and then examined for different haematological parameters. The data obtained was statistically analysed.Results: While there has been a sequential rise of fetal red cell count, hemoglobin and the total white cell count neutrophils with gestational age, the mean corpuscular cell volume decreased. All these values were comprised to varying degrees in maternal diseases except for nucleated rell blood cells which conspicuously increased in neonates of diabetic mothers.Conclusions: In this study, a small attempt was made to assess the haematological profile (including alkali resistant hemoglobin) of the newborns in relation to gestational age and maternal diseases in the population attending a tertiary care hospital in Eastern India.

Assessment of Haematological and Biochemical Parameters of Women at Childbirth and their Newborn in Abidjan, Côte d’ Ivoire

“…In addition, fetal-maternal blood exchange, through the umbilical cord, may also contribute to Lawton et al (2015), reported that newborn blood volume increases when umbilical cord clamping is not done immediately after childbirth. Such results concerning erythrocyte parameters in newborns are also reported by Bhattacharya et al (2017). In addition, the mean values of leukocytes, eosinophils, lymphocytes and monocytes of the newborns were significantly higher (p<0.01) than those of women at childbirth.…”