1979
DOI: 10.1016/s0140-6736(79)92745-4
|View full text |Cite
|
Sign up to set email alerts
|

Copper/Zinc Superoxide Dismutase Activity in Trisomy 21 by Translocation

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

3
3
0
1

Year Published

1981
1981
2003
2003

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 17 publications
(7 citation statements)
references
References 5 publications
3
3
0
1
Order By: Relevance
“…8, has no effect on the SOD-I gene expression. This finding confirms the reports of some recent investigations concerning the SOD-1 level in cases of trisomy 21 by translocation (Garber et al 1979, Emberger et al 1980, Crosti et al 1981 and also in the case of trisomy 21 by mirror duplication (Turleau et al 1980).…”
Section: Discussionsupporting
confidence: 91%
See 3 more Smart Citations
“…8, has no effect on the SOD-I gene expression. This finding confirms the reports of some recent investigations concerning the SOD-1 level in cases of trisomy 21 by translocation (Garber et al 1979, Emberger et al 1980, Crosti et al 1981 and also in the case of trisomy 21 by mirror duplication (Turleau et al 1980).…”
Section: Discussionsupporting
confidence: 91%
“…The excess of SOD-I in regular trisomy 21 patients has been confirmed. The gene dosage for this enzyme is the same as reported previously by Garber et al (1979) and Emberger et al (1980), among others. SOD-1 activity in red blood cells in cases of translocation trisomy 21 t(q21q21) was also observed to be elevated in both patients tested.…”
Section: Discussionsupporting
confidence: 84%
See 2 more Smart Citations
“…Presume-se que o fenótipo nesta trissomia seja resultante da expressão de certos genes encontrados no cromossomo 21, 1 principalmente como conseqüência da duplicação da região 21q22, 2 onde se localiza o gene que codifica a superóxido dismutase-1(SOD-1). [3][4][5][6][7][8][9] A cópia extra do gene da superóxido dismutase-1 (SOD-1) confere aos portadores da Síndrome de Down uma atividade da enzima aumentada em 50% em diferentes tipos de células -eritrócitos, leucócitos, plaquetas e fibroblastos.…”
Section: Introductionunclassified