1986
DOI: 10.1007/978-1-4613-2179-8_34
|View full text |Cite
|
Sign up to set email alerts
|

Down’s Syndrome and Alzheimer’s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders?

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
1
0

Year Published

1987
1987
1997
1997

Publication Types

Select...
3

Relationship

0
3

Authors

Journals

citations
Cited by 3 publications
(1 citation statement)
references
References 62 publications
0
1
0
Order By: Relevance
“…The overexpression of the CuZnSOD gene could disturb the steady-state equilibrium of active oxygen species within the cell, resulting in oxidative damage to biologically important molecules (10,11). It has been suggested that such a mechanism may be responsible for or contributory to either the mental retardation or Alzheimer disease, or both, which are part of the DS phenotype (12)(13)(14)(15).…”
mentioning
confidence: 99%
“…The overexpression of the CuZnSOD gene could disturb the steady-state equilibrium of active oxygen species within the cell, resulting in oxidative damage to biologically important molecules (10,11). It has been suggested that such a mechanism may be responsible for or contributory to either the mental retardation or Alzheimer disease, or both, which are part of the DS phenotype (12)(13)(14)(15).…”
mentioning
confidence: 99%