This paper discusses a statistical effect of performance optimization to uncertainty in circuit delay. Performance optimization has an effect of balancing the delay of each path in a circuit, i.e. the delay of long paths are shortened and the delay of short paths are lengthened. In these path-balanced circuits, the uncertainty in circuit delay, which are caused by delay calculation error, manufacturing variability, fluctuation of operating condition, etc., becomes worse by a statistical characteristic of delay. Thus, a highly-optimized circuit may not satisfy delay constraints. In this paper, we demonstrate some examples that uncertainty in circuit delay is increased by path-balancing, and we then raise a problem that performance optimization increases statisticallydistributed circuit delay.