Conventional detection of 2,4-dinitrophenol using quartz crystal microbalance

Park, Jong-Won; Kurosawa, Shigeru; Aizawa, Hitoshi; Han, Dae-Sang; Yoshimoto, Minoru; Nakamura, Chikashi; Miyake, Jun; Chang, Sang‐Mok

doi:10.1109/tuffc.2003.1182123

Cited by 12 publications

(1 citation statement)

References 8 publications

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“…The other is a chemical approach using the sandwich reaction with immunized latex particles. Amplified signals could be obtained due to increasing mass through double-layer binding when immunized latex particles were bound via DNP-BSA after competitive reaction [20].…”

Section: Study Of Detection Conditions For a Dioxin Model Compound Us...mentioning

confidence: 99%

Immunosensors using a quartz crystal microbalance

Kurosawa

Aizawa

Tozuka

et al. 2003

Meas. Sci. Technol.

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Better analytical technology has been demanded for accurate and rapid determination of trace amounts of chemical compounds, such as marker proteins for disease or endocrine disrupters like dioxin, which might be contained in blood, food and the environment. The study of immunosensors using a quartz crystal microbalance (QCM) has recently focused on conventional detection methods for the determination of chemical compounds together with the development of reagents and processes. This paper introduces the principle of the detection method of QCM immunosensors developed at AIST and its application to the detection of trace amounts of chemical compounds.

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Section: Study Of Detection Conditions For a Dioxin Model Compound Us...mentioning

confidence: 99%

Immunosensors using a quartz crystal microbalance

Kurosawa

Aizawa

Tozuka

et al. 2003

Meas. Sci. Technol.

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A survey of the 2001 to 2005 quartz crystal microbalance biosensor literature: applications of acoustic physics to the analysis of biomolecular interactions

Cooper¹,

Singleton²

2007

J of Molecular Recognition

335

205

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The widespread exploitation of biosensors in the analysis of molecular recognition has its origins in the mid-1990s following the release of commercial systems based on surface plasmon resonance (SPR). More recently, platforms based on piezoelectric acoustic sensors (principally 'bulk acoustic wave' (BAW), 'thickness shear mode' (TSM) sensors or 'quartz crystal microbalances' (QCM)), have been released that are driving the publication of a large number of papers analysing binding specificities, affinities, kinetics and conformational changes associated with a molecular recognition event. This article highlights salient theoretical and practical aspects of the technologies that underpin acoustic analysis, then reviews exemplary papers in key application areas involving small molecular weight ligands, carbohydrates, proteins, nucleic acids, viruses, bacteria, cells and lipidic and polymeric interfaces. Key differentiators between optical and acoustic sensing modalities are also reviewed.

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