Controlling magnesium corrosion and degradation-regulating mineralization using matrix GLA protein

Hong, Dandan; Zaky, Samer H.; Chong, Rong; Lukashova, Lyudmila; Beniash, Elia; Verdelis, Kostas; Witte, Frank; Sfeir, Charles

doi:10.1016/j.actbio.2019.05.048

Cited by 8 publications

(2 citation statements)

References 37 publications

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“…The treated sample also shows a thin uniform deposition over the surface and was analyzed by FTIR as shown in figure 3. The bare magnesium alloy had no significant peaks for the range 500 to 4000 cm −1 , indicating that no functional groups were present on the surface [20,33,34]. The FTIR spectra of acid pickled sample exhibits a peak at 2921 cm −1 which matches with C-H stretching and another peak at 1405 cm −1 attributed to C-H bending.…”

Section: Surface Morphology and Characterisationmentioning

confidence: 99%

Tailoring biomineralization and biodegradation of Mg–Ca alloy by acetic acid pickling

Rahim

Joseph

Hanas

2020

Mater. Res. Express

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Magnesium and its alloys are suitable candidates for developing biodegradable metallic implants. However, the rapid degradation of these alloys in the physiological environment is a major limitation for such applications. In this work, Mg-Ca alloy was chemically treated with acetic acid and its effects on degradation behaviour were studied using simulated body fluid (SBF). The surface morphology and composition of the acid pickled samples were investigated using a scanning electron microscope (SEM) and infrared spectroscopy (IR). The degradation rate was analysed by conducting potentiodynamic polarization (PDP) and immersion tests. The results show that optimum acetic acid treatment improved the corrosion resistance by acid etching and formation of magnesium acetate layer. The treated samples also exhibited enhanced biomineralization and developed calcium phosphate layer on the surfaces during immersion tests. It is proposed that acetic acid pickling can be used as a reliable technique for surface modification as well as for pre-treatment of magnesium alloys to make them suitable for degradable metallic implant applications.

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Section: Surface Morphology and Characterisationmentioning

confidence: 99%

Tailoring biomineralization and biodegradation of Mg–Ca alloy by acetic acid pickling

Rahim

Joseph

Hanas

2020

Mater. Res. Express

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“…The presence of chloride ions usually leads to accelerated corrosion [ 19 ], since the formation of MgCl 2 releases OH − ions from the precipitation layer (5), which in turn can react with the dissolved Mg 2+ ions, while phosphates and carbonates may promote the formation of protective or partially protective corrosion products [ 12 ]. The presence of organic components, such as proteins, cells, or bacteria, can additionally affect the corrosion reaction [ 20 ]. Compared to room temperature, the body temperature of 37 °C can accelerate the corrosion reaction on the one hand and modify it to some extent on the other, since the solubility of calcium phosphate is also dependent on the temperature [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods

Zhang

Zimmermann

Müeller

et al. 2022

Bioactive Materials

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Magnesium as biodegradable biomaterial could serve as bone augmentation material in implant dentistry. The knowledge about the predictability of the biodegradation process is essential as this process needs to go hand in hand with the formation of new bone to gradually replace the augmentation material. Therefore, this work aimed to assess if the electrochemistry (EC) measurements of the corrosion process correlate with the surface features at various time points during the surface degradation, in order to describe the degradation process of Mg and Mg alloys more reliably, under the assumption that differences in EC behavior can be detected and related to specific patterns on the surface. In this test setup, a special optical chamber was used for electrochemical measurements on Mg and Mg-alloys (Mg2Ag, Mg4Ag, and Mg6Ag). Specimens were investigated using different circulating cell culture solutions as electrolytes, these were minimum essential medium (MEM), Hank's Balanced Salt Solution (HBSS), and MEM+ (MEM with added sodium hydrogen carbonate) at 37 °C. Open circuit potential measurements (OCP) over 30 min followed by cyclic polarization were performed. The electrochemistry data, including OCP, exchange current density and corrosion potential, were compared with visible changes at the surface during these treatments over time. The results show that the addition of silver (Ag) leads to a “standardization” of the degradation regardless of the selected test medium. It is currently difficult to correlate the visible microscopic changes with the data taken from the measurements. Therefore, further investigations are necessary.

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Biodegradable Metals

Witte¹

2020

Biomaterials Science

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Controlling magnesium corrosion and degradation-regulating mineralization using matrix GLA protein

Cited by 8 publications

References 37 publications

Tailoring biomineralization and biodegradation of Mg–Ca alloy by acetic acid pickling

Tailoring biomineralization and biodegradation of Mg–Ca alloy by acetic acid pickling

Exploring the degradation behavior of MgXAg alloys by in vitro electrochemical methods

Biodegradable Metals

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