In this study, we have designed and assessed a Ketorolac tromethamine (KT) based thermally responsive in situocular gelling system. These gelling systems consist of a thermally responsive in situ gelling polymer, poloxamer 407 (PM) and different molecular weight of poly (vinyl alcohol) (PVA) as release retardant. The formulations were analyzed for sol-gel transition temperature, gelling aptitude, viscosity and rheological studies, gel morphology study, gel dissolution property and in vitro drug release study. FTIR spectral analysis was performed to explore any polymer-polymer or drug-polymer association. In comparison to commercially available drugs, the new formulations present a longer-lasting drug release profile.